[HTML][HTML] Natural history studies and clinical trial readiness for genetic developmental and epileptic encephalopathies

EE Palmer, K Howell, IE Scheffer - Neurotherapeutics, 2021 - Elsevier
The developmental and epileptic encephalopathies (DEEs) are the most severe group of
epilepsies. They usually begin in infancy or childhood with drug-resistant seizures …

[HTML][HTML] EEG biomarkers for the diagnosis and treatment of infantile spasms

B Romero Milà, K Remakanthakurup Sindhu… - Frontiers in …, 2022 - frontiersin.org
Early diagnosis and treatment are critical for young children with infantile spasms (IS), as
this maximizes the possibility of the best possible child-specific outcome. However, there are …

Landscape of genetic infantile epileptic spasms syndrome—A multicenter cohort of 124 children from India

B Nagarajan, VK Gowda, S Yoganathan… - Epilepsia …, 2023 - Wiley Online Library
Objective Literature on the genotypic spectrum of Infantile Epileptic Spasms Syndrome
(IESS) in children is scarce in developing countries. This multicentre collaboration evaluated …

Hope in the uncertainties and certainty for parents of children with rare neurological disorders. Part I (of 3): Uncertainty

EE Palmer, R Sachdev, E Beavis… - … of Paediatrics and …, 2022 - Wiley Online Library
This is the first of three articles exploring the aspects of clinical care for children with rare
neurological disorders including uncertainties old and new. The disruptive technologies of …

[HTML][HTML] Epilepsy and neurodevelopmental outcomes in a cohort of West syndrome beyond two years of age

R Aramanadka, JK Sahu, P Madaan… - Indian journal of …, 2022 - Springer
Objective To determine epilepsy and neurodevelopmental outcomes beyond 2 y of age and
their putative prognostic factors in children with West syndrome (WS). Methods This cross …

Management of west syndrome during COVID-19 pandemic: a viewpoint from South Asian west syndrome research group

JK Sahu, P Madaan, P Chand, A Kumar, K Linn… - Epilepsy Research, 2020 - Elsevier
In the wake of the pandemic COVID-19 and nationwide lockdowns gripping many countries
globally, the national healthcare systems are either overwhelmed or preparing to combat …

Delays to care in infantile epileptic spasms syndrome: Racial and ethnic inequities

CB Abath, N Gupta, A Hadjinicolaou, S Donatelli… - …, 2024 - Wiley Online Library
Abstract Objective Non‐Hispanic (NH) Black children are less likely to receive a standard
treatment course for infantile epileptic spasms syndrome (IESS) than White/NH children at …

Classifying etiology of infantile spasms syndrome in resource‐limited settings: A study from the South Asian region

J Wanigasinghe, JK Sahu, P Madaan, K Fatema… - Epilepsia …, 2021 - Wiley Online Library
Objective Etiological classification of infantile spasms syndrome (ISS) is important,
considering the influence on prognosis based on the presence or absence of a known …

Long-term survival and factors associated with mortality among children with infantile epileptic spasms syndrome–A retrospective cohort study

M Iype, TS Anish, G Saradakutty, PAM Kunju… - … : European Journal of …, 2023 - Elsevier
Background and objectives The existing literature indicates a higher risk of mortality among
children with Infantile epileptic spasms syndrome (IESS). Our aim was to find the mortality …

[HTML][HTML] Automatic BASED scoring on scalp EEG in children with infantile spasms using convolutional neural network

Y Fan, D Chen, H Wang, Y Pan, X Peng… - Frontiers in Molecular …, 2022 - frontiersin.org
In recent years, the Burden of Amplitudes and Epileptiform Discharges (BASED) score has
been used as a reliable, accurate, and feasible electroencephalogram (EEG) grading scale …