Accumulating studies indicate that long non-coding RNAs (lncRNAs) play important roles in
the regulation of diverse biological processes involved in homeostatic control of the vessel …

Highlights•Exosomal microRNAs are pivotal regulators of angiogenesis during wound
healing.•Exosomal microRNAs regulate VEGF expression and downstream signaling …

Diabetic wounds represent a significant healthcare burden and are characterized by
impaired wound healing due to increased oxidative stress and persistent inflammation. We …

Diabetic nephropathy (DN) is a common kidney disease in people with diabetes, which is
also a serious microvascular complication of diabetes and the main cause of end-stage …

Vascular endothelial cells (VECs) that form the inner wall of blood vessels can be injured by
high glucose-induced autophagy and apoptosis. Although the role of long noncoding RNA …

There is a strong unmet need for new therapeutics to accelerate wound healing across both
chronic and acute indications. It is well established that local tissue hypoxia, vascular …

Diabetic patients are frequently affected by coronary microvascular dysfunction (CMD), a
condition consisting of a combination of altered vasomotion and long-term structural change …

The vascular endothelium acts as a barrier between the blood flow and the inner lining of
the vessel wall, and it functions as a filtering machinery to filter out any unwanted transfer of …

Introduction: Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and is
considered to be a sterile inflammatory disease. Increasing evidence suggest that pyroptosis …

Objective—In response to tissue injury, the appropriate progression of events in
angiogenesis is controlled by a careful balance between pro and antiangiogenic factors. We …