Diabetic retinopathy (DR) is the most common complication of diabetes. It is also the main
cause of blindness caused by multicellular damage involving retinal endothelial cells …

Mechanistic/mammalian target of rapamycin (mTOR), an atypical serine/threonine kinase of
the phosphoinositide 3‐kinase‐(PI3K‐) related kinase family, elicits a vital role in diverse …

Through a number of biochemical and structural processes, long-term exposure to a diabetic
environment causes alterations in bone metabolism and poor bone micro-architecture …

Background Active peptides play a vital role in the development of new drugs and the
identification and discovery of drug targets. As the first reported native peptide homodimer …

Diabetes-associated atherosclerosis involves excessive immune cell recruitment and
plaque formation. However, the mechanisms remain poorly understood. Transcriptomic …

Type 2 diabetes is often complicated with hypertension, such that 73.6% of patients≥ 18
years with type 2 diabetes also have hypertension. With increasing age, the risk of …

Retinal cell damage caused by diabetes leads to retinal microvascular injury. Roundabout 4
(ROBO4) is involved in angiogenesis, which varies with the development of diabetic …

Diabetic retinopathy (DR) is the leading cause of vision loss among older adults. The goal of
this case-control study was to identify circulating miRNAs for the diagnosis of DR. The …

The aim of the study was to demonstrate how transthyretin (TTR) could affect long non-
coding RNA (lncRNA) of maternally expressed gene 3 (MEG3) and play important roles in …

Diabetes mellitus is a metabolic disorder that increases fracture risk and interferes with bone
formation and impairs fracture healing. Genomic studies on diabetes and fracture healing …