Paclitaxel is one of the most effective chemotherapeutic drugs which processes the obvious
curative effect for a broad range of cancers including breast, ovarian, lung, and head & neck …

Chemotherapy resistance remains a major challenge in the treatment of gynecologic
malignancies. Increasing evidence suggests that circular RNAs (circRNAs) play a significant …

Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The
mechanisms by which paclitaxel is transported into neurons, which are essential for …

Paclitaxel (PTX) is an anticancer drug used to treat solid tumors, but one of its common
adverse effects is chemotherapy-induced peripheral neuropathy (CIPN). Currently, there is …

Pain is a clinical condition that is currently of great concern and is often caused by tissue or
nerve damage or occurs as a concomitant symptom of a variety of diseases such as cancer …

Chemotherapy-induced neuropathic pain (CINP) is one of the most prominent and
incapacitating complication associated with chemotherapeutic regimens. The exact …

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent and dose-
limiting complications in chemotherapy patients. One identified mechanism underlying CIPN …

Nociceptive hypersensitivity is a significant side effect with the chronic administration of
opioids as well as chemotherapeutics. Both opioid-induced hypersensitivity (OIH) and …

Cannabidiol (CBD), a cannabinoid that does not create psychoactive activities, has been
identified as having a multitude of therapeutic benefits. This study delves into the chemical …

BACKGROUND: Paclitaxel (PTX), which is a first-line chemotherapy drug used to treat
various types of cancers, exhibits peripheral neuropathy as a common side effect that is …