Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Pseudomonas aeruginosa (P. aeruginosa) is a ubiquitous and opportunistic microorganism
and is considered one of the most significant pathogens that produce chronic colonization …

Pseudomonas aeruginosa is a leading cause of chronic respiratory infections in people with
cystic fibrosis (CF), bronchiectasis or chronic obstructive pulmonary disease (COPD), and …

Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Chronic airway colonisation by Pseudomonas aeruginosa, a hallmark of cystic fibrosis (CF)
lung disease, is associated with increased morbidity and mortality and despite aggressive …

Within-host adaptation is a hallmark of chronic bacterial infections, involving substantial
genomic changes. Recent large-scale genomic data from prolonged infections allow the …

Highlights•Pseudomonas aeruginosa in CF airways: paradigm of bacterial microevolution.•
Evolution within CF host triggers conversions of genotype and phenotype.•Severity of lung …

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …

Pseudomonas aeruginosa biofilms contribute heavily to chronic lung infection in cystic
fibrosis patients, leading to morbidity and mortality. Nitric oxide (NO) has been shown to …

Healthcare-associated infections are major causes of complications that lead to extended
hospital stays and significant medical costs. The use of medical devices, including catheters …