The melanocortin system consists of melanocortin peptides derived from the
proopiomelanocortin gene, five melanocortin receptors, two endogenous antagonists, and …

The melanocortins (α, β and γ-melanocyte-stimulating hormones: MSHs;
adrenocorticotrophic hormone: ACTH), a family of pro-opiomelanocortin (POMC)-derived …

The feasibility of SOMAscan, a multiplex, high sensitivity proteomics platform, for use in
studies using archived plasma samples has not yet been assessed. We quantified 1,305 …

Context: Administration of retinol-binding protein 4 (RBP-4) impairs insulin sensitivity in
animals, and elevated serum concentrations have been associated with insulin resistance in …

Biological age (BA), derived from molecular and physiological measurements, has been
proposed to better predict mortality and disease than chronological age (CA). In the present …

Agouti-related protein (AGRP) plays a key role in energy homeostasis. The carboxyl-
terminal domain of AGRP acts as an endogenous antagonist of the melanocortin-4 receptor …

A number of different neuropeptides exert powerful concerted controls on feeding behavior
and energy balance, most of them being produced in hypothalamic neuronal networks …

The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food
intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency …

Obesity has become one of the most significant public health problems facing the world
today. However, the pathogenesis of obesity is multifactorial and involves the interaction of …

Objective: In our study, we aimed to evaluate eating-attitudes in adult-ADHD, and to
examine its relationship with sociodemographic, clinical, AgRP, and biochemical …