[HTML][HTML] Recent advances in the surface functionalization of PLGA-based nanomedicines
MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
The role of cell‐penetrating peptides in potential anti‐cancer therapy
M Zhou, X Zou, K Cheng, S Zhong, Y Su… - Clinical and …, 2022 - Wiley Online Library
Due to the complex physiological structure, microenvironment and multiple physiological
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site …
mRNA vaccine in cancer therapy: Current advance and future outlook
Y Li, M Wang, X Peng, Y Yang, Q Chen… - Clinical and …, 2023 - Wiley Online Library
Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that
have shown great promise in the immunotherapy of a wide variety of infectious diseases and …
have shown great promise in the immunotherapy of a wide variety of infectious diseases and …
Functionalized peptide-based nanoparticles for targeted cancer nanotherapeutics: A state-of-the-art review
Cancer mortality is increasing at an alarming rate across the globe. Albeit, many
therapeutics are available commercially, they are not effective and have no cure up to today …
therapeutics are available commercially, they are not effective and have no cure up to today …
Peptide-containing nanoformulations: Skin barrier penetration and activity contribution
T Zhang, X Luo, K Xu, W Zhong - Advanced Drug Delivery Reviews, 2023 - Elsevier
Transdermal drug delivery presents a less invasive pathway, circumventing the need to pass
through the gastrointestinal tract and liver, thereby reducing drug breakdown, initial …
through the gastrointestinal tract and liver, thereby reducing drug breakdown, initial …
Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …
disorder affecting millions of people worldwide. Despite current treatment options, many …
[HTML][HTML] 9S1R nullomer peptide induces mitochondrial pathology, metabolic suppression, and enhanced immune cell infiltration, in triple-negative breast cancer …
N Ali, C Wolf, S Kanchan, SR Veerabhadraiah… - Biomedicine & …, 2024 - Elsevier
Nullomers are the shortest strings of absent amino acid (aa) sequences in a species or
group of species. Primes are those nullomers that have not been detected in the genome of …
group of species. Primes are those nullomers that have not been detected in the genome of …
Emerging concepts in designing next-generation multifunctional nanomedicine for cancer treatment
K Chakraborty, A Tripathi, S Mishra… - Bioscience …, 2022 - portlandpress.com
Nanotherapy has emerged as an improved anticancer therapeutic strategy to circumvent the
harmful side effects of chemotherapy. It has been proven to be beneficial to offer multiple …
harmful side effects of chemotherapy. It has been proven to be beneficial to offer multiple …
[图书][B] CPP, cell-penetrating peptides
Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …
Mitochondria-targeted cancer therapy based on functional peptides
Y Sun, H Zhang, G Lu, H Wang, Y Lu, L Fan - Chinese Chemical Letters, 2023 - Elsevier
Mitochondria are critical for tumor growth and metastasis. A number of traditional antitumor
drugs have poor water solubility and must penetrate multiple cellular barriers to reach the …
drugs have poor water solubility and must penetrate multiple cellular barriers to reach the …