EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force

EFNS Task Force on Diagnosis and … - European journal of …, 2012 - Wiley Online Library
Background: The evidence base for the diagnosis and management of amyotrophic lateral
sclerosis (ALS) is weak. Objectives: To provide evidence‐based or expert recommendations …

Amyotrophic lateral sclerosis

JD Mitchell, GD Borasio - The lancet, 2007 - thelancet.com
Amyotrophic lateral sclerosis (known in the UK as motor neuron disease) is a devastating
illness with uncertain pathogenesis. In this Seminar, we review its natural history, clinical …

Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial

SC Bourke, M Tomlinson, TL Williams… - The Lancet …, 2006 - thelancet.com
Background Few patients with amyotrophic lateral sclerosis currently receive non-invasive
ventilation (NIV), reflecting clinical uncertainty about the role of this intervention. We aimed …

Amyotrophic lateral sclerosis: improving care with a multidisciplinary approach

A Hogden, G Foley, RD Henderson… - Journal of …, 2017 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease, leading to
death within an average of 2–3 years. A cure is yet to be found, and a single disease …

End-of-life management in patients with amyotrophic lateral sclerosis

S Connolly, M Galvin, O Hardiman - The Lancet Neurology, 2015 - thelancet.com
Most health-care professionals are trained to promote and maintain life and often have
difficulty when faced with the often rapid decline and death of people with terminal illnesses …

Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease

A Radunovic, D Annane, MK Rafiq… - Cochrane Database …, 2017 - cochranelibrary.com
Background Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is a
fatal neurodegenerative disease. Neuromuscular respiratory failure is the most common …

Pain in amyotrophic lateral sclerosis

A Chiò, G Mora, G Lauria - The Lancet Neurology, 2017 - thelancet.com
Pain is a largely neglected symptom in patients with amyotrophic lateral sclerosis (ALS)
although it is reported by most of these patients. It occurs at all stages of the disease and can …

Dysarthria in amyotrophic lateral sclerosis: A review

B Tomik, RJ Guiloff - Amyotrophic Lateral Sclerosis, 2010 - Taylor & Francis
Dysarthria is a motor disorder of speech characterized by abnormalities of the articulation
and intelligibility of speech. Phonation and the rate of facial movements may also be …

Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease

L Ng, F Khan, CA Young… - Cochrane Database of …, 2017 - cochranelibrary.com
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease - Ng, L - 2017 |
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EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives: An evidence‐based review with …

PM Andersen, GD Borasio, R Dengler… - European journal of …, 2005 - Wiley Online Library
Despite being one of the most devastating diseases known, there is little evidence for
diagnosing and managing patients with amyotrophic lateral sclerosis (ALS). Although …