The blood-brain barrier (BBB) plays a vital role in regulating the trafficking of fluid, solutes
and cells at the blood-brain interface and maintaining the homeostatic microenvironment of …

Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological
disorders, whose complex relationship is not completely understood. Cerebrovascular …

Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

A blood-brain barrier (BBB) on a chip similar to the in vivo BBB is important for evaluating
the efficacy of reparative cell therapeutics for ischemic stroke in vitro. In this study, we …

Schizophrenia is a debilitating psychiatric illness that remains poorly understood. While the
bulk of symptomatology has classically been associated with disrupted brain functioning …

Background The traditional Chinese medicine Cistanche deserticola has been reported to
be valid for cardiovascular and cerebrovascular diseases. However, its active components …

Organophosphate (OP) poisoning can trigger cholinergic crisis, a life-threatening toxidrome
that includes seizures and status epilepticus. These acute toxic responses are associated …

Acute organophosphate (OP) intoxication can trigger seizures that progress to status
epilepticus (SE), and survivors often develop chronic morbidities, including spontaneous …

Stroke is a leading cause of morbidity and mortality globally. Leonurine (also named SCM‐
198), a compound extracted from Herba leonuri, was effective on the prevention of various …

Methamphetamine (METH) abuse causes serious health problems worldwide, and long-
term use of METH disrupts the blood–brain barrier (BBB). Herein, we explored the potential …