Acute kidney injury in the critically ill: an updated review on pathophysiology and management
P Pickkers, M Darmon, E Hoste, M Joannidis… - Intensive care …, 2021 - Springer
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …
Paradigms of acute kidney injury in the intensive care setting
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
[HTML][HTML] Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the
classification and management of acute kidney injury (AKI). The guideline was derived from …
classification and management of acute kidney injury (AKI). The guideline was derived from …
Worsening renal function in patients with acute heart failure undergoing aggressive diuresis is not associated with tubular injury
Background: Worsening renal function (WRF) in the setting of aggressive diuresis for acute
heart failure treatment may reflect renal tubular injury or simply indicate a hemodynamic or …
heart failure treatment may reflect renal tubular injury or simply indicate a hemodynamic or …
Subphenotypes in critical care: translation into clinical practice
Despite progress in the supportive care available for critically ill patients, few advances have
been made in the search for effective disease-modifying therapeutic options. The fact that …
been made in the search for effective disease-modifying therapeutic options. The fact that …
Targeting acute kidney injury in COVID-19
JA Kellum, JWO van Till… - Nephrology Dialysis …, 2020 - academic.oup.com
Abstract As of 15 August 2020, Coronavirus disease 2019 (COVID-19) has been reported
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …
in> 21 million people world-wide and is responsible for more than 750,000 deaths. The …
Acute kidney injury and progression of diabetic kidney disease
SMW Yu, JV Bonventre - Advances in chronic kidney disease, 2018 - Elsevier
Diabetic kidney disease, commonly termed diabetic nephropathy (DN), is the most common
cause of end-stage kidney disease (ESKD) worldwide. The characteristic histopathology of …
cause of end-stage kidney disease (ESKD) worldwide. The characteristic histopathology of …
Conceptual advances and evolving terminology in acute kidney disease
Over the past decade, new insights into epidemiology, pathophysiology and biomarkers
have modified our understanding of acute kidney dysfunction and damage, and their …
have modified our understanding of acute kidney dysfunction and damage, and their …
The cardiorenal syndrome in heart failure
MR Costanzo - Heart Failure Clinics, 2020 - heartfailure.theclinics.com
This discussion is focused on the interactions during acute and chronic heart failure (HF)
between heart and kidney, which are highly interdependent in health and disease. In normal …
between heart and kidney, which are highly interdependent in health and disease. In normal …
Identification of acute kidney injury subphenotypes with differing molecular signatures and responses to vasopressin therapy
PK Bhatraju, LR Zelnick, J Herting, R Katz… - American journal of …, 2019 - atsjournals.org
Rationale: Currently, no safe and effective pharmacologic interventions exist for acute
kidney injury (AKI). One reason may be that heterogeneity exists within the AKI population …
kidney injury (AKI). One reason may be that heterogeneity exists within the AKI population …