The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

The Vaginal Microenvironment: The Physiologic Role of Lactobacilli

E Amabebe, DOC Anumba - Frontiers in medicine, 2018 - frontiersin.org
In addition to being a passage for sperm, menstruum, and the baby, the human vagina and
its microbiota can influence conception, pregnancy, the mode and timing of delivery, and the …

A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

ME Perez-Muñoz, MC Arrieta, AE Ramer-Tait, J Walter - microbiome, 2017 - Springer
After more than a century of active research, the notion that the human fetal environment is
sterile and that the neonate's microbiome is acquired during and after birth was an accepted …

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

DM Chu, J Ma, AL Prince, KM Antony, MD Seferovic… - Nature medicine, 2017 - nature.com
Human microbial communities are characterized by their taxonomic, metagenomic and
metabolic diversity, which varies by distinct body sites and influences human physiology …

The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …

Rebuilding the gut microbiota ecosystem

A Gagliardi, V Totino, F Cacciotti, V Iebba… - International journal of …, 2018 - mdpi.com
A microbial ecosystem in which bacteria no longer live in a mutualistic association is called
dysbiotic. Gut microbiota dysbiosis is a condition related with the pathogenesis of intestinal …

Viable bacterial colonization is highly limited in the human intestine in utero

E Rackaityte, J Halkias, EM Fukui, VF Mendoza… - Nature medicine, 2020 - nature.com
Mucosal immunity develops in the human fetal intestine by 11–14 weeks of gestation, yet
whether viable microbes exist in utero and interact with the intestinal immune system is …

[HTML][HTML] Antibiotics and the human gut microbiome: dysbioses and accumulation of resistances

MP Francino - Frontiers in microbiology, 2016 - frontiersin.org
The human microbiome is overly exposed to antibiotics, due, not only to their medical use,
but also to their utilization in farm animals and crops. Microbiome composition can be rapidly …

[HTML][HTML] The healthy human blood microbiome: fact or fiction?

DJ Castillo, RF Rifkin, DA Cowan… - Frontiers in cellular and …, 2019 - frontiersin.org
The blood that flows perpetually through our veins and arteries performs numerous functions
essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates …

Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …