Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin

K Aloss, P Hamar - Pharmaceutics, 2023 - mdpi.com
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

A review on nanotechnology: Properties, applications, and mechanistic insights of cellular uptake mechanisms

S Khan, S Mansoor, Z Rafi, B Kumari, A Shoaib… - Journal of Molecular …, 2022 - Elsevier
Nanotechnology is a relatively new field of science and technology that studies tiny objects
(0.1–100 nm). Due to various positive attributes displayed by the biogenic synthesis of …

A new theranostic pH-responsive niosome formulation for doxorubicin delivery and bio-imaging against breast cancer

S Saharkhiz, A Zarepour, A Zarrabi - International Journal of Pharmaceutics, 2023 - Elsevier
As one of the newest generations of nanoplatforms, smart nanotheranostics have attracted
signifivant attentions for medical applications, especially in oncology and cancer treatment …

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation

M Hashemi, F Ghadyani, S Hasani, Y Olyaee… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

Antigen‐Capturing Dendritic‐Cell–Targeting Nanoparticles for Enhanced Tumor Immunotherapy Based on Photothermal‐Therapy–Induced In Situ Vaccination

Y Li, Y Luo, L Hou, Z Huang, Y Wang… - Advanced healthcare …, 2023 - Wiley Online Library
In situ vaccines have revolutionized immunotherapy as they can stimulate tumor‐specific
immune responses, with the cancer being the antigen source. However, the heterogeneity of …

[HTML][HTML] Lipid-hybrid cell-derived biomimetic functional materials: A state-of-the-art multifunctional weapon against tumors

WS Liu, LL Wu, CM Chen, H Zheng, J Gao, ZM Lu… - Materials Today Bio, 2023 - Elsevier
Tumors are among the leading causes of death worldwide. Cell-derived biomimetic
functional materials have shown great promise in the treatment of tumors. These materials …

Structural modification and strategies for the enhanced doxorubicin drug delivery

SA Khan, MJ Akhtar - Bioorganic Chemistry, 2022 - Elsevier
Doxorubicin belongs to the anthracycline chemical class of the drug and is one of the widely
used anticancer drugs. The common side effects of doxorubicin include vomiting, hair loss …

[HTML][HTML] pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment

SS Nunes, SEM Miranda, J de Oliveira Silva… - Biomedicine & …, 2021 - Elsevier
Irinotecan (IRN) is a semisynthetic derivative of camptothecin that acts as a topoisomerase I
inhibitor. IRN is used worldwide for the treatment of several types of cancer, including …

Gastrointestinal digestive fate of whey protein isolate coated liposomes loading astaxanthin: Lipolysis, release, and bioaccessibility

L Pan, H Li, L Hou, Z Chang, Y Li, X Li - Food Bioscience, 2022 - Elsevier
Abstracts Whey protein isolate coated astaxanthin-loaded liposomes were prepared in this
work. The gastrointestinal digestive fate of whey protein isolate coated astaxanthin-loaded …