Perioperative pain management is a significant challenge following major spine surgery.
Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and …

Background Dexmedetomidine decreases cardiac complications in adults undergoing
cardiovascular surgery. This systematic review assessed whether perioperative …

Background The surgical stress response plays an important role on the pathogenesis of
perioperative cardiac complications. Alpha‐2 adrenergic agonists attenuate this response …

Purpose This systematic review and meta-analysis appraise the clinical evidence on efficacy
and safety of dexmedetomidine (DEX), as a sedative and analgesic adjunct in adult patients …

BACKGROUND Catheter-related bladder discomfort (CRBD) due to an indwelling urinary
catheter causes postoperative distress. Dexmedetomidine is used as an anaesthetic …

Background: Anesthesia for craniotomies should blunt responses to noxious stimuli,
whereas subsequently leaving patients sufficiently alert for early neurological evaluation …

Background: We conducted a randomized trial to evaluate the opioid-sparing effect of an
intraoperative infusion of dexmedetomidine (DEX) after craniotomy. Methods: Sixty adult …

Arrhythmias are the common complications following cardiac surgery and contribute to
hemodynamic instability, cognitive impairment, thromboembolic events, and congestive …

Background We hypothesized that the addition of dexmedetomidine in a clinically relevant
dose to propofol-remifentanil anesthesia regimen does not exert an adverse effect on motor …

Evidence-based standardization of the perioperative management of patients undergoing
complex spine surgery can improve outcomes such as enhanced patient satisfaction …