Tissue Models for Neisseria gonorrhoeae Research—From 2D to 3D

M Heydarian, E Rühl, R Rawal… - Frontiers in Cellular and …, 2022 - frontiersin.org
Neisseria gonorrhoeae is a human-specific pathogen that causes gonorrhea, the second
most common sexually transmitted infection worldwide. Disease progression, drug …

Role of Pili in the Virulence of Neisseria gonorrhoeae

AP Punsalang Jr, WD Sawyer - Infection and immunity, 1973 - Am Soc Microbiol
Gonococci of the colonial types that are associated with virulence, types 1 and 2, have pili
that enable the bacteria both to attach in vitro to human epithelial cells and to resist …

Interactions of Neisseria gonorrhoeae with Adherent Polymorphonuclear Leukocytes

MP Simons, WM Nauseef, MA Apicella - Infection and immunity, 2005 - Am Soc Microbiol
Neisseria gonorrhoeae causes severe exudative urethritis. The exudates from infected
individuals contain large numbers of polymorphonuclear leukocytes (PMN) with ingested …

Double immunofluorescence microscopic technique for accurate differentiation of extracellularly and intracellularly located bacteria in cell culture

J Heesemann, R Laufs - Journal of clinical microbiology, 1985 - Am Soc Microbiol
A double immunofluorescence staining technique is described for differentiation between
cell-attached (extracellular) and ingested (intracellular) bacteria by HEp-2 cells in cell …

Phagocyte strategy vs. microbial tactics

P Densen, GL Mandell - Reviews of infectious diseases, 1980 - JSTOR
We are constantly in contact with a vast array of microorganisms living in our external
environ-ment as well as on our own mucosal surfaces. The overwhelming majority of these …

Host Defense Against Neisseria meningitidis Requires a Complement-Dependent Bactericidal Activity

A Nicholson, IH Lepow - Science, 1979 - science.org
Some individuals, with severe or recurrent infection with Neisseria species, have been
identified as lacking a component in the terminal attack sequence of complement …

Studies on the Virulence of Neisseria gonorrhoeae I. Relation of Colonial Morphology and Resistance to Phagocytosis by Polymorphonuclear Leukocytes

C Thongthai, WD Sawyer - Infection and Immunity, 1973 - Am Soc Microbiol
Colonial varieties of Neisseria gonorrhoeae that are associated with virulence, types 1 and
2, were more resistant to phagocytosis by rabbit exudative polymorphonuclear leukocytes …

Attachment and ingestion of gonococci human neutrophils

JA Dilworth, JO Hendley, GL Mandell - Infection and immunity, 1975 - Am Soc Microbiol
Previous studies have indirectly shown that type 1 gonococci are more resistant to
phagocytosis by human neutrophils (PMN) than type 3 gonococci. Using phase contrast …

[HTML][HTML] Protective role of Toll-like receptor 4 in experimental gonococcal infection of female mice

M Packiam, H Wu, SJ Veit, N Mavrogiorgos… - Mucosal …, 2012 - Elsevier
Neisseria gonorrhoeae is a common bacterial sexually transmitted infection. Like all Gram-
negative bacteria, the outer membrane of the gonococcus is rich in endotoxin, a known …

Pathogenesis and immunology of experimental gonococcal infection: role of iron in virulence

SM Payne, RA Finkelstein - Infection and Immunity, 1975 - Am Soc Microbiol
Addition of iron componds to inocula of the relatively avirulent T3 or T4 colony types of
gonococci increased their lethality for chicken embryos after intravenous inoculation but had …