Colorimetric and fluorescent sensors for detection of nerve agents and organophosphorus pesticides

Q Chen, Y Sun, S Liu, J Zhang, C Zhang… - Sensors and Actuators B …, 2021 - Elsevier
Organophosphorus compounds are toxic organic phosphorus molecules including nerve
agents and pesticides. Organophosphorus pesticides play a significant role in improving …

Dual use of artificial-intelligence-powered drug discovery

F Urbina, F Lentzos, C Invernizzi, S Ekins - Nature machine intelligence, 2022 - nature.com
Dual use of artificial-intelligence-powered drug discovery | Nature Machine Intelligence Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

Organophosphorus chemical security from a peaceful perspective: Sustainable practices in its synthesis, decontamination and detection

VB Silva, YH Santos, R Hellinger, S Mansour… - Green …, 2022 - pubs.rsc.org
Organophosphorus compounds play an important role in the modern chemical industry and
have a broad range of applications as flame retardants, agrochemicals, and chemical …

Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease

KI Eissa, MM Kamel, LW Mohamed… - Drug Development …, 2023 - Wiley Online Library
A series of 12 S‐substituted tetrahydrobenzothienopyrimidines were designed and
synthesized based on the donepezil scaffold. All the newly synthesized compounds were …

Visual and rapid detection of nerve agent mimics in gas and solution phase by a simple fluorescent probe

Q Chen, J Liu, S Liu, J Zhang, L He, R Liu… - Analytical …, 2023 - ACS Publications
Chemical nerve agents are highly toxic organophosphorus compounds that are easy to
obtain and can be utilized by terrorists to threaten homeland security and human safety …

Dense Conductive Metal–Organic Frameworks as Robust Electrocatalysts for Biosensing

K Niu, P Sun, J Chen, X Lu - Analytical Chemistry, 2022 - ACS Publications
Due to the fascinating properties such as high porosity, large surface areas, and tunable
chemical components, metal–organic frameworks (MOFs) have emerged in many fields …

2D conductive covalent organic frameworks with abundant carbonyl groups for electrochemical sensing

K Niu, Y Zhang, J Chen, X Lu - ACS sensors, 2022 - ACS Publications
Due to their permanent porosity, robust chemical stability, and tunable structure, covalent
organic frameworks (COFs) are very attractive in the application of energy storage, catalysis …

Counteracting poisoning with chemical warfare nerve agents

N Maček Hrvat, Z Kovarik - Arhiv za higijenu rada i toksikologiju, 2020 - hrcak.srce.hr
Sažetak Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents
(NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter …

Neurosteroids as novel anticonvulsants for refractory status epilepticus and medical countermeasures for nerve agents: A 15-year journey to bring ganaxolone from …

DS Reddy - Journal of Pharmacology and Experimental …, 2024 - ASPET
This article describes recent advances in the use of neurosteroids as novel anticonvulsants
for refractory status epilepticus (RSE) and as medical countermeasures (MCs) for …

[HTML][HTML] Fluorescent probes for the detection of chemical warfare agents

WQ Meng, AC Sedgwick, N Kwon, M Sun… - Chemical Society …, 2023 - pubs.rsc.org
Chemical warfare agents (CWAs) are toxic chemicals that have been intentionally
developed for targeted and deadly use on humans. Although intended for military targets …