B cells have important functions in the pathogenesis of autoimmune diseases, including
autoimmune rheumatic diseases. In addition to producing autoantibodies, B cells contribute …

Systemic lupus erythematosus (SLE) is a severe multisystem autoimmune disease that can
cause injury in almost every body system. While considered a classic example of …

B cells have a prominent role in the pathogenesis of systemic lupus erythematosus (SLE).
They are mediators of inflammation through the production of pathogenic antibodies that …

B cell hyperactivity and breach of tolerance constitute hallmarks of systemic lupus
erythematosus (SLE). The heterogeneity of disease manifestations and relatively rare …

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
affecting multiple organ systems that runs an unpredictable course and may present with a …

B cell hyperactivity is a hallmark of the complex autoimmune disease systemic lupus
erythematosus (SLE), which has justified drug development focusing on B cell altering …

Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

CD22 and Siglec-G are members of the Siglec family. Both are inhibitory co-receptors on the
surface of B cells and inhibit B-cell receptor induced signaling, characterized by inhibition of …

Systemic lupus erythematosus (SLE) is a systemic autoimmune condition characterised by a
wide spectrum of clinical manifestations, partly related to the disease itself, but also linked to …

Abstract Currently, Systemic Lupus Erythematosus (SLE) therapies range from antimalarials
to glucocorticoids, in addition to immunosupressive agents or biologics such as rituximab or …