Modulation of Cholesterol metabolism with Phytoremedies in Alzheimer's disease: A comprehensive Review

S Koppula, NL Wankhede, SS Sammeta… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a complex neurological ailment that causes cognitive decline
and memory loss. Cholesterol metabolism dysregulation has emerged as a crucial element …

Mitochondrial translation failure represses cholesterol gene expression via Pyk2-Gsk3β-Srebp2 axis

T Toshima, M Yagi, Y Do, H Hirai… - Life Science …, 2024 - life-science-alliance.org
Neurodegenerative diseases and other age-related disorders are closely associated with
mitochondrial dysfunction. We previously showed that mice with neuron-specific deficiency …