Purpose: To evaluate the accuracy of conventional and new methods of Papanicolaou (Pap)
testing when used to detect cervical cancer and its precursors. Data Sources: Systematic …

ObjectiveTo provide evidence-based consensus guidelines for the management of women
with cervical cytological abnormalities and cervical cancer precursors. ParticipantsA panel of …

ContextA Papanicolaou (Pap) test result of atypical squamous cells of undetermined
significance (ASCUS) presents a clinical challenge. Only 5% to 10% of women with ASCUS …

The histopathological classification of a disease should reflect both current concepts of its
pathogenesis as well as its clinical behavior. Over the last 50 years our understanding of the …

Background: The appropriate management of women with minor cytologic lesions in their
cervix is unclear. We performed a meta-analysis to assess the accuracy of human …

Background Atypical squamous cells of undetermined significance (ASCUS) and low‐grade
squamous intra‐epithelial lesions (LSIL) are minor lesions of the cervical epithelium …

ContextEvery year approximately 2 million US women are diagnosed as having a cervical
cytological result of atypical squamous cells of undetermined significance (ASC-US) …

The objective of this study was to develop a comprehensive natural history model of human
papillomavirus (HPV) and cervical cancer using a two-step approach to model calibration. In …

Vaccines for preventing human papillomavirus (HPV) infection are far along in clinical
development and testing and hold great promise for reducing HPV infections and HPV …

Objectives. Human papillomavirus (HPV) infection is a sexually transmitted disease (STD)
and the single most important etiological agent of cervical cancer. In parallel with the …