COVID-19 and immunomodulation in IBD

MF Neurath - Gut, 2020 - gut.bmj.com
The current coronavirus pandemic is an ongoing global health crisis due to COVID-19,
caused by severe acute respiratory syndrome coronavirus 2. Although COVID-19 leads to …

Hepatitis B virus persistence and reactivation

Y Shi, M Zheng - bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

ECCO guidelines on the prevention, diagnosis, and management of infections in inflammatory bowel disease

T Kucharzik, P Ellul, T Greuter, JF Rahier… - Journal of Crohn's …, 2021 - academic.oup.com
The introduction and broad use of new immunosuppressive agents, including biologic
agents and JAK inhibitors, have revolutionised treatment of inflammatory bowel disease …

Management of patients with Crohn's disease and ulcerative colitis during the coronavirus disease-2019 pandemic: results of an international meeting

DT Rubin, MT Abreu, V Rai, CA Siegel, V Ahuja… - …, 2020 - gastrojournal.org
The 2020 annual meeting for IOIBD was scheduled to occur in March, but was cancelled
owing to the emergence of COVID-19. Given how this disease might affect patients with IBD …

[HTML][HTML] Korean clinical practice guidelines on biologics and small molecules for moderate-to-severe ulcerative colitis

SY Na, CH Choi, EM Song, KB Bang… - Intestinal …, 2023 - synapse.koreamed.org
Ulcerative colitis (UC), a relapsing-remitting chronic inflammatory bowel disease (IBD), has
a variable natural course but potentially severe disease course. Since the development of …

The thrilling journey of SARS-CoV-2 into the intestine: from pathogenesis to future clinical implications

F Scaldaferri, G Ianiro, G Privitera… - Inflammatory Bowel …, 2020 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has a direct
impact on the gastrointestinal system, as up to 50% of fecal samples from coronavirus …

Overall and comparative safety of biologic and immunosuppressive therapy in inflammatory bowel diseases

A Holmer, S Singh - Expert review of clinical immunology, 2019 - Taylor & Francis
Introduction: Efficacy and safety are key aspects when choosing therapies for patients with
inflammatory bowel diseases (IBD). While several randomized trials and indirect …

latent tuberculosis in patients with inflammatory bowel diseases receiving immunosuppression—risks, screening, diagnosis and management

SR Fehily, AH Al‐Ani, J Abdelmalak… - Alimentary …, 2022 - Wiley Online Library
Background One quarter of the world's population has latent tuberculosis infection (LTBI).
Systemic immunosuppression is a risk factor for LTBI reactivation and the development of …

The safety profile of vedolizumab in ulcerative colitis and Crohn's disease: 4 years of global post-marketing data

RD Cohen, F Bhayat, A Blake… - Journal of Crohn's and …, 2020 - academic.oup.com
Abstract Background and Aims Vedolizumab is a gut-selective antibody to α 4 β 7 integrin,
approved to treat moderate-to-severe ulcerative colitis and Crohn's disease in adults …