Stroke is one of the leading causes of death and disability in the world, of which ischemia
accounts for the majority. There is growing evidence of changes in synaptic connections and …

Astrocytes, as the most abundant glial cells in the central nervous system, are tightly
integrated into neural networks and participate in numerous aspects of brain physiology and …

Due to global population aging and modern lifestyle changes, the incidence of central
nervous system (CNS) disorders, such as neurodegenerative diseases, neuropsychiatric …

Glial cells expressing neuron‐glial antigen 2 (NG2), also known as oligodendrocyte
progenitor cells (OPCs), play a critical role in maintaining brain health. However, their ability …

The integrity of the blood‐brain barrier (BBB) is mainly maintained by endothelial cells and
basement membrane and could be regulated by pericytes, neurons, and glial cells including …

Traumatic brain injury (TBI) is one of the most common pathological conditions impacting the
central nervous system (CNS). A neurological deficit associated with TBI results from a …

Parkinson's disease (PD) is the most common movement disorder and the second most
prevalent neurodegenerative disease after Alzheimer's disease. Despite decades of …

Background Galectin-3 acts as a mediator of microglial inflammatory response following
stroke injury. However, it remains unclear whether inhibiting galectin-3 protects against …

Stroke is ranked as the second leading cause of death worldwide and a major cause of long-
term disability. A potential therapeutic target that could offer favorable outcomes in stroke is …

Background and purpose Cerebral ischemia‒reperfusion injury causes significant harm to
human health and is a major contributor to stroke-related deaths worldwide. Current …