The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Parkinson's disease (PD) usually presents in older adults and typically has both motor and
non-motor dysfunctions. PD is a progressive neurodegenerative disorder resulting from …

Polycystic ovary syndrome (PCOS) is a common female condition typified by reproductive,
hyperandrogenic, and metabolic features. Polycystic ovary syndrome is a genetic condition …

Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …

Exercise is fundamental for good health, whereas physical inactivity underpins many chronic
diseases of modern society. It is well appreciated that regular exercise improves metabolism …

Globally, depression is a leading cause of disability and has remained so for decades.
Antidepressant medications have suboptimal outcomes and are too frequently associated …

Abstract Purpose of Review For many years, exercise was controversial in multiple sclerosis
(MS) and thought to exacerbate symptoms and fatigue. However, having been found to be …