Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

With the decline in the number of new Severe Acute Respiratory Syndrome Coronavirus 2
(SARS‐CoV‐2) infections, the World Health Organization announced the end of the SARS …

Amyotrophic lateral sclerosis (ALS) is a fatal multisystem disease characterized by
progressive death of motor neurons, loss of muscle mass, and impaired energy metabolism …

Translocator protein (TSPO), a 18 kDa protein found in the outer mitochondrial membrane,
has historically been associated with the transport of cholesterol in highly steroidogenic …

Pineal melatonin and the cortisol awakening response (CAR) are integral aspects of the
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neuromuscular disease that
results in the loss of motor neurons and severe skeletal muscle atrophy. The etiology of ALS …

Mitochondria are critical cellular energy resources and are central to the life of the neuron.
Mitophagy selectively clears damaged or dysfunctional mitochondria through autophagic …

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease which damages
upper and lower motor neurons (UMN and LMN) innervating the muscles of the trunk …

Mitochondrial dysfunction represents one of the most common molecular hallmarks of both
sporadic and familial forms of amyotrophic lateral sclerosis (ALS), a neurodegenerative …

Mitochondria have been the focus of extensive research for decades since their dysfunction
is linked to more than 150 distinct human disorders. Despite considerable efforts …