Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Fungi have evolved unique metabolic regulation mechanisms for adapting to the changing
environments. One of the key features of fungal adaptation is the production of secondary …

Climate change affects all aspects of ecosystems, including humans and numerous
microorganisms. Fungi are especially sensitive to climate extremes. Persistently warmer …

Climate change has been proposed as a set of factors that affect the frequency, distribution,
and morbimortality of many infectious diseases, in which mycosis has also been impacted …

Candida auris has been described as an emerging yeast species during the last decade. As
many as 25% of its strains may naturally exhibit multi-drug resistance to the currently …

We previously reported that administration of Cryptococcus neoformans Δsgl1 mutant
vaccine, accumulating sterylglucosides (SGs) and having normal capsule (GXM), protects …

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines
are currently available in humans mainly because opportunistic mycoses generally occur …

Highlights•AFPs are promising sources of new antifungal agents.•The physiochemical and
biological properties of AFPs often need to be improved.•Rational design and combinatorial …

Candida albicans, a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human
health and disease. As a commensal organism, it normally resides harmlessly within the …

The Global Action Fund for Fungal Infections (GAFFI) estimates that fungal diseases kill
around 150 people each hour, and yet they are globally overlooked and neglected …