[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

Rheumatoid arthritis: advances in treatment strategies

P Prasad, S Verma, Surbhi, NK Ganguly… - Molecular and cellular …, 2023 - Springer
Rheumatoid arthritis (RA) is characterised by severe joint and bone damage due to
heightened autoimmune response at the articular sites. Worldwide annual incidence and …

Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis

MH Buch, S Eyre, D McGonagle - Nature Reviews Rheumatology, 2021 - nature.com
Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

[HTML][HTML] Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

[HTML][HTML] Etiology and risk factors for rheumatoid arthritis: a state-of-the-art review

VC Romão, JE Fonseca - Frontiers in medicine, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …

[HTML][HTML] Yoga maintains Th17/Treg cell homeostasis and reduces the rate of T cell aging in rheumatoid arthritis: a randomized controlled trial

S Gautam, R Kumar, U Kumar, S Kumar, K Luthra… - Scientific Reports, 2023 - nature.com
The pathogenesis of rheumatoid arthritis (RA) is characterized by a Th17/Treg cell
imbalance. A pro-inflammatory cytokine milieu that promotes the continued proliferation of …

[HTML][HTML] Academic Textbook: The Role of Melatonin in Pathogenesis and Treatment of Autoimmune Diseases

SOH Tabatabaei, R Moazamiyanfar, AM Fard… - Kindle, 2022 - preferpub.org
An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

[HTML][HTML] DNA methylation as a future therapeutic and diagnostic target in rheumatoid arthritis

M Ciechomska, L Roszkowski, W Maslinski - Cells, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a long-term autoimmune disease of unknown etiology that leads
to progressive joint destruction and ultimately to disability. RA affects as much as 1% of the …