COPD is a clinically heterogeneous syndrome characterized by injury to airways, airspaces,
and lung vasculature and usually caused by tobacco smoke and/or air pollution exposure …

Objectives: The objective of this study was to evaluate an artificial intelligence (AI)-based
prototype algorithm for the fully automated per lobe segmentation and emphysema …

Spirometry is the current gold standard for diagnosing and monitoring the progression of
Chronic Obstructive Pulmonary Disease (COPD). However, many current and former …

Background The mechanisms underlying airflow obstruction in COPD cannot be
distinguished by standard spirometry. We ascertain whether mathematical modeling of …

Rationale and Objectives To evaluate the role of radiomics based on Chest Computed
Tomography (CT) in the identification and severity staging of chronic obstructive pulmonary …

Airway wall thickening in cigarette smokers is thought to be a result of inflammatory changes
and airway remodeling. This study investigates if CT-derived airway wall thickening …

Background The correlation between visual emphysema patterns and subsequent
progression of disease may provide a way to enrich a study population for treatment trials of …

Background Spirometry confers limited value for identifying small-airway disorders (SADs) in
early-stage COPD, which can be detected with impulse oscillometry (IOS) and …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Background There are similarities and differences between chronic obstructive pulmonary
disease (COPD) and asthma patients in terms of computed tomography (CT) disease …