Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI

JPB O'Connor, SP Robinson… - The British journal of …, 2019 - academic.oup.com
Hypoxia is known to be a poor prognostic indicator for nearly all solid tumours and also is
predictive of treatment failure for radiotherapy, chemotherapy, surgery and targeted …

Functional imaging of the lungs with gas agents

SJ Kruger, SK Nagle, MJ Couch, Y Ohno… - Journal of Magnetic …, 2016 - Wiley Online Library
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings

Y Ohno, JB Seo, G Parraga, KS Lee, WB Gefter… - Radiology, 2021 - pubs.rsna.org
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …

Using Pulmonary Imaging to Move Chronic Obstructive Pulmonary Disease beyond FEV1

HO Coxson, J Leipsic, G Parraga… - American journal of …, 2014 - atsjournals.org
FEV1, measured using spirometry, provides a straightforward, widely available, and
inexpensive global measurement of airflow limitation and lung function. For decades, FEV1 …

Free-breathing Dynamic 19F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD

M Gutberlet, TF Kaireit, A Voskrebenzev, F Lasch… - Radiology, 2018 - pubs.rsna.org
Purpose To quantify regional lung ventilation in patients with chronic obstructive pulmonary
disease (COPD) by using free-breathing dynamic fluorinated (fluorine 19 [19F]) gas …

New and current clinical imaging techniques to study chronic obstructive pulmonary disease

HO Coxson, J Mayo, S Lam, G Santyr… - American journal of …, 2009 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized
by both small airway and parenchymal abnormalities. There is increasing evidence to …

Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes

EA Hoffman, DA Lynch, RG Barr… - Journal of Magnetic …, 2016 - Wiley Online Library
Pulmonary x‐ray computed tomographic (CT) and magnetic resonance imaging (MRI)
research and development has been motivated, in part, by the quest to subphenotype …

Update on the roles of distal airways in COPD

PR Burgel, A Bourdin, P Chanez… - European …, 2011 - Eur Respiratory Soc
This review is the summary of a workshop on the role of distal airways in chronic obstructive
pulmonary disease (COPD), which took place in 2009 in Vence, France. The evidence …

Oxygen-enhanced magnetic resonance imaging versus computed tomography: multicenter study for clinical stage classification of smoking-related chronic obstructive …

Y Ohno, T Iwasawa, JB Seo, H Koyama… - American journal of …, 2008 - atsjournals.org
Rationale: Oxygen-enhanced magnetic resonance imaging (MRI) has been proposed as a
useful tool for assessing regional morphological and functional changes in chronic …

T2* Measurements of 3-T MRI With Ultrashort TEs: Capabilities of Pulmonary Function Assessment and Clinical Stage Classification in Smokers

Y Ohno, H Koyama, T Yoshikawa… - American Journal of …, 2011 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to determine the usefulness of MRI with
ultrashort TEs on a 3-T system and of thin-section MDCT for pulmonary function assessment …