[HTML][HTML] Flavonoids enhance rod opsin stability, folding, and self-association by directly binding to ligand-free opsin and modulating its conformation
Rhodopsin (Rho) is a visual G protein–coupled receptor expressed in the rod
photoreceptors of the eye, where it mediates transmission of a light signal into a cell and …
photoreceptors of the eye, where it mediates transmission of a light signal into a cell and …
[HTML][HTML] The impact of CASR A990G polymorphism in response to cinacalcet treatment in hemodialysis patients with secondary hyperparathyroidism
J Ngamkam, S Vadcharavivad, N Areepium… - Scientific Reports, 2021 - nature.com
The objective of this study was to determine the impact of calcium sensing receptor (CASR)
A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to …
A990G genetic polymorphism on parathyroid hormone (PTH) lowering response to …
Pharmacogenetic role of vitamin D-binding protein and vitamin D receptor polymorphisms in the treatment response of dialysis patients with secondary …
R de Alarcon, B Alburquerque-Gonzalez… - Nephrology Dialysis …, 2022 - academic.oup.com
Secondary hyperparathyroidism (SHPT) is common in chronic kidney disease (CKD) and
dialysis patients, and results in renal osteodystrophy, thus causing the decreased synthesis …
dialysis patients, and results in renal osteodystrophy, thus causing the decreased synthesis …
[HTML][HTML] Pharmacogenetic and safety analysis of cinacalcet hydrochloride in healthy Chinese subjects
YJ Liu, LN Sun, ZP Cheng, Y Qian, ZQ Ma… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Our study aims to explore the effect of genetics on the pharmacodynamics (PD)
and pharmacokinetics (PK) of cinacalcet in healthy Chinese subjects; to investigate the …
and pharmacokinetics (PK) of cinacalcet in healthy Chinese subjects; to investigate the …
[PDF][PDF] 活性维生素D 联合西那卡塞治疗慢性肾衰竭透析患者继发甲状旁腺功能亢进疗效及对TGF-β1 和sTfR 水平的影响
张文博， 霍延红， 焦娟， 张鑫， 牛红心 - 河北医学, 2019 - hbyxzzs.cn
目的: 观察活性维生素D 联合西那卡塞治疗慢性肾衰竭透析患者继发甲状旁腺功能亢进(SHPT)
的疗效及对血清转化生长因子-β1 (TGF-β1) 和血清转铁蛋白受体(sTfR) 水平的影响ꎮ 方法: 90 …
的疗效及对血清转化生长因子-β1 (TGF-β1) 和血清转铁蛋白受体(sTfR) 水平的影响ꎮ 方法: 90 …
The Calcium‐Sensing Receptor (CaSR) in Disease
Summary Calcium (Ca 2+) is fundamental to organic life, and the ability to detect and
respond to changes in extracellular Ca 2+ ions (Ca 2+ o) is paramount to all living …
respond to changes in extracellular Ca 2+ ions (Ca 2+ o) is paramount to all living …
Effects of the CASR rs104893706 (A843E) gain-of-function mutation on bone mineral density in postmenopausal women by advanced age and smoking
ÖK Gömleksiz, AB Teker, F Yanar, E Aslan… - İstanbul Journal of …, 2022 - dergipark.org.tr
Background and Aims: The G protein-coupled calcium-sensing receptor (CaSR) plays an
important role in extracellular cal-cium homeostasis and regulation of parathyroid hormone …
important role in extracellular cal-cium homeostasis and regulation of parathyroid hormone …
[PDF][PDF] Relationship of calcium-sensing receptor gene polymorphism CASR rs 1042636, CASR rs 1802757, and cinacalcet response among Egyptian hemodialysis …
MA Behairy, SM Shawky, SAEH Bawady… - Journal of Parathyroid …, 2024 - researchgate.net
Introduction: Secondary hyperparathyroidism (SHPT) is a common complication associated
with morbidity and mortality among hemodialysis (HD) patients. Objectives: The current …
with morbidity and mortality among hemodialysis (HD) patients. Objectives: The current …
The potential of pharmacogenomics to advance kidney disease treatment
KA Birdwell, CP Chung - Clinical Journal of the American Society …, 2017 - journals.lww.com
Identifying factors underlying the variable and often unpredictable response to drugs
remains one of the most complex challenges facing modern therapeutics (1). Commonly …
remains one of the most complex challenges facing modern therapeutics (1). Commonly …
[PDF][PDF] Jaruwan Ngamkam1, Somratai Vadcharavivad1Ε, Nutthada Areepium1, Titinun Auamnoy2, Kullaya Takkavatakarn3, Pisut Katavetin3, Khajohn …
K Praditpornsilpa, S Eiam‑Ong… - Scientific Reports, 2021 - academia.edu
Results Characteristics of the study population. A total of 135 Thai HD patients with SHPT
participated in this study (Fig. 1). The characteristics of the participants are summarized in …
participated in this study (Fig. 1). The characteristics of the participants are summarized in …