Despite being a biological waste, human urine contains a small population of cells with self-
renewal capacity and differentiation potential into several cell types. Being derived from the …

A key element of risk assessment is accounting for the full range of variability in response to
environmental exposures. Default dose-response methods typically assume a 10-fold …

Substantial production and wide applications of engineered nanomaterials (ENMs) have
raised concerns over their potential influences on the environment and humans. However …

Currently, toxicological testing of food contact materials (FCMs) is focused on single
substances and their genotoxicity. However, people are exposed to mixtures of chemicals …

Background: The Next Generation (NexGen) of Risk Assessment effort is a multi-year
collaboration among several organizations evaluating new, potentially more efficient …

The pharmaceutical industry is continuing to face high research and development (R&D)
costs and low overall success rates of clinical compounds during drug development. There …

In this work, we present eMolTox, a web server for the prediction of potential toxicity
associated with a given molecule. A total of 174 toxicology-related in vitro/vivo experimental …

Introduction Modern drug discovery is generally accessed by useful information from
previous large databases or uncovering novel data. The lack of biological and/or chemical …

Pharmaceutical drug analysis (PDA), besides quantifying drugs and related substances
(RS), can enrich drug discovery (DD) by suggesting new leads. PDA may be extended …

Safety sciences and the identification of chemical hazards have been seen as one of the
most immediate practical applications of human pluripotent stem cell technology. Protocols …