Obesity and metabolic disorders are of great societal concern and generate substantial
human health care costs globally. Interventions have resulted in only minimal impacts on …

A microfluidic multi-organ chip emulates the tissue culture microenvironment, enables
interconnection of organ equivalents and overcomes interspecies differences, making this …

Cigarette smoke (CS) has been reported to increase predisposition to oral cancer and is
also recognized as a risk factor for many conditions including periodontal diseases …

Drug-induced liver injury (DILI) remains a leading reason why new compounds are dropped
from further study or are the subject of product warnings and regulatory actions. Hy's Law of …

Methyl paraben (MP) is an endocrine‐disrupting compound that possesses estrogenic
properties and contributes to an aberrant burden of estrogen signaling in the human breast …

Endocrine disruptor compounds (EDCs) are environment chemicals that cause harmful
effects through multiple mechanisms, interfering with hormone system resulting in alteration …

Chemicals induce liver cancer in rodents through well characterized adverse outcome
pathways (AOPs). We hypothesized that measurement of molecular initiating events (MIEs) …

Metal-oxide nanoparticles find widespread applications in mundane life today, and cost-
effective evaluation of their cytotoxicity and ecotoxicity is essential for sustainable progress …

Toxicity studies in mammals continue to be the most appropriate model for predicting risk in
humans, but they tend to be expensive and time-consuming. In the aftermath of the genetic …

FutureTox IV, a Society of Toxicology Contemporary Concepts in Toxicology workshop, was
held in November 2018. Building upon FutureTox I, II, and III, this conference focused on the …