Quinazoline derivatives: synthesis and bioactivities
D Wang, F Gao - Chemistry Central Journal, 2013 - Springer
Owing to the significant biological activities, quinazoline derivatives have drawn more and
more attention in the synthesis and bioactivities research. This review summarizes the …
more attention in the synthesis and bioactivities research. This review summarizes the …
Microwave-assisted synthesis of quinazolines and quinazolinones: an overview
L Mohammadkhani, MM Heravi - Frontiers in chemistry, 2020 - frontiersin.org
Microwave irradiation (MWI), as a unique, effective, sustainable, more economic, and
greener source of energy compared to conventional heating, is applied in different organic …
greener source of energy compared to conventional heating, is applied in different organic …
Antiproliferative, antiangiogenic and apoptotic effect of new hybrids of quinazoline-4 (3H)-ones and sulfachloropyridazine
SS Zahran, FA Ragab, MG El-Gazzar… - European Journal of …, 2023 - Elsevier
Three new sets of quinazolinones bearing sulfachloropyridazine 4a-f, 6a-i and 8a-i were
designed and synthesized. All the synthesized compounds were screened for their in vitro …
designed and synthesized. All the synthesized compounds were screened for their in vitro …
In-silico activity prediction, structure-based drug design, molecular docking and pharmacokinetic studies of selected quinazoline derivatives for their antiproliferative …
Background Cancer is a major health threat especially in unindustrialized nations. It
surpasses coronary diseases and takes the number one killer position as a result of different …
surpasses coronary diseases and takes the number one killer position as a result of different …
Synthesis of 2-aryl quinazolinones via iron-catalyzed cross-dehydrogenative coupling (CDC) between N–H and C–H bonds
Herein, we describe the direct synthesis of quinazolinones via cross-dehydrogenative
coupling between methyl arenes and anthranilamides. The C–H functionalization of the …
coupling between methyl arenes and anthranilamides. The C–H functionalization of the …
[HTML][HTML] Synthesis and anticancer activity of new quinazoline derivatives
HA Abuelizz, M Marzouk, H Ghabbour… - Saudi Pharmaceutical …, 2017 - Elsevier
In this study, a new series of quinazoline derivatives (3–26) was synthesized and
characterized via physicochemical and spectral means. Treatment of 2-amino-5 …
characterized via physicochemical and spectral means. Treatment of 2-amino-5 …
Synthesis and anticancer activity of N-substituted 2-arylquinazolinones bearing trans-stilbene scaffold
A novel series of 2-arylquinazolinones 7a-o bearing trans-stilbene moiety were designed,
synthesized, and evaluated against human breast cancer cell lines including human breast …
synthesized, and evaluated against human breast cancer cell lines including human breast …
Synthesis of novel tetrazole derivatives and evaluation of their antifungal activity
E Łukowska-Chojnacka, J Mierzejewska… - Bioorganic & Medicinal …, 2016 - Elsevier
With the appearance of the antifungal resistance, novel antifungal agents need to be
identified. In this context new 2, 5-disubstituted tetrazole derivatives containing …
identified. In this context new 2, 5-disubstituted tetrazole derivatives containing …
Recent Advances and Developments of in vitro Evaluation of Heterocyclic Moieties on Cancer Cell Lines
Besides worthy development in cancer therapy, cancer is still one of the leading causes of
death, worldwide. The future burden of cancer will probably be even larger because people …
death, worldwide. The future burden of cancer will probably be even larger because people …
Dry and wet lab analysis on benzofused heterocyclic compounds as effective corrosion inhibitors for mild steel in acidic medium
The influence of two benzofused heterocyclic compounds, namely 2-phenylquinazolin-4
(3H)-one (PQO) and 2-phenyl-4H-benzo [d] oxazin-4-one (POO) in controlling mild steel …
(3H)-one (PQO) and 2-phenyl-4H-benzo [d] oxazin-4-one (POO) in controlling mild steel …