It is well known that phenotype of animals may be modified by the nutritional modulations
through epigenetic mechanisms. As a key and central component of epigenetic network …

Disturbed epigenetic mechanisms, which developmentally regulate gene expression via
modifications to DNA, histone proteins, and chromatin, have been hypothesized to play a …

Background Folate and its synthetic form folic acid function as donor of one-carbon units and
have been, together with other B-vitamins, implicated in programming of epigenetic …

In the modern world, cardiovascular disorders are the leading cause of mortality in
developed countries, which in most cases undergo a long subclinical phase that can last …

Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food
constituents, which can transfer information from the external environment and influence …

Alterations of epigenetic marks are linked to normal development and cellular differentiation
as well as to the progression of common chronic diseases. The plasticity of these marks …

Both life span and health span are influenced by genetic, environmental and lifestyle factors.
With the genetic influence on human life span estimated to be about 20–25%, epigenetic …

In multicellular organisms, all the cells are genetically identical but turn genes on or off at the
right time to promote differentiation into specific cell types. The regulation of higher-order …

Pregnancy is a vital time of growth and development during which maternal nutrition
significantly influences the future health of both mother and baby. During pregnancy, the …

Abstract Background Cadmium (Cd), lead (Pb) and arsenic (As) are common environmental
contaminants that have been associated with lower birthweight. Although some essential …