KMT2A: Umbrella Gene for Multiple Diseases

S Castiglioni, E Di Fede, C Bernardelli, A Lettieri… - Genes, 2022 - mdpi.com
KMT2A (Lysine methyltransferase 2A) is a member of the epigenetic machinery, encoding a
lysine methyltransferase responsible for the transcriptional activation through lysine 4 of …

Dietary and supplemental maternal methyl-group donor intake and cord blood DNA methylation

S Pauwels, M Ghosh, RC Duca, B Bekaert, K Freson… - Epigenetics, 2017 - Taylor & Francis
Maternal nutrition is critically involved in the development and health of the fetus. We
evaluated maternal methyl-group donor intake through diet (methionine, betaine, choline …

How the Mediterranean diet and some of its components modulate inflammatory pathways in arthritis

F Oliviero, P Spinella, U Fiocco, R Ramonda… - Swiss medical …, 2015 - smw.ch
Arthritis encompasses a heterogeneous group of diseases characterised by inflammation
that leads not only to joint damage, bone erosion, severe pain and disability, but also affects …

Endothelial dysfunction in individuals born after fetal growth restriction: cardiovascular and renal consequences and preventive approaches

C Yzydorczyk, JB Armengaud, AC Peyter… - … origins of health and …, 2017 - cambridge.org
Individuals born after intrauterine growth restriction (IUGR) have an increased risk of
perinatal morbidity/mortality, and those who survive face long-term consequences such as …

Can metabolically healthy obesity be explained by diet, genetics, and inflammation?

E Navarro, AN Funtikova, M Fíto… - Molecular nutrition & …, 2015 - Wiley Online Library
A substantial proportion of obese individuals do not present cardiometabolic complications
such as diabetes, hypertension, or dyslipidemia. Some, but not all, prospective studies …

Resource allocation and compensation during development in holometabolous insects

D Nestel, NT Papadopoulos… - Journal of Insect …, 2016 - Elsevier
We provide an extensive review on current knowledge and future research paths on the
topic of resource allocation and compensation during development in holometabolous …

Rheumatoid arthritis and periodontitis–inflammatory and infectious connections. Review of the literature

GR Persson - Journal of oral microbiology, 2012 - Taylor & Francis
An association between oral disease/periodontitis and rheumatoid arthritis (RA) has been
considered since the early 1820s. The early treatment was tooth eradication …

Diet and aging

S Ribarič - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Nutrition has important long‐term consequences for health that are not only limited to the
individual but can be passed on to the next generation. It can contribute to the development …

Human cytochrome P450 epoxygenases: variability in expression and role in inflammation-related disorders

P Shahabi, G Siest, UA Meyer… - Pharmacology & …, 2014 - Elsevier
Beyond their contribution to the metabolism of xenobiotics, cytochrome P450 (CYP)
epoxygenases are actively involved in the metabolism of endogenous substances, like …

Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients …

Q Wang, J Ye, D Fang, L Lv, W Wu, D Shi, Y Li, L Yang… - Bmc Microbiology, 2020 - Springer
Background The human gut microbiome plays a critical role in the carcinogenesis of
colorectal cancer (CRC). However, a comprehensive analysis of the interaction between the …