Transgenerational epigenetic inheritance of diabetes risk as a consequence of early nutritional imbalances
JC Jimenez-Chillaron, M Ramon-Krauel… - Proceedings of the …, 2016 - cambridge.org
In today's world, there is an unprecedented rise in the prevalence of chronic metabolic
diseases, including obesity, insulin resistance and type 2 diabetes (T2D). The pathogenesis …
diseases, including obesity, insulin resistance and type 2 diabetes (T2D). The pathogenesis …
Antioxidant diets and functional foods promote healthy aging and longevity through diverse mechanisms of action
S Wichansawakun, HS Buttar - The role of functional food security in global …, 2019 - Elsevier
It is well recognized that humans are enjoying longer life spans than their ancestors.
However, longevity has resulted in a larger geriatric population worldwide, posing an …
However, longevity has resulted in a larger geriatric population worldwide, posing an …
Early determinants of cardiovascular disease
According to the Developmental Origins of Health and Disease hypothesis intrauterine or
postnatal adaptations to the environment causes morphologic, physiologic or metabolic …
postnatal adaptations to the environment causes morphologic, physiologic or metabolic …
Long term effects of pre-and early postnatal nutrition and environment on the gut
JP Lalles - Journal of Animal Science, 2012 - academic.oup.com
Abstract The Developmental Origins of Health and Disease hypothesis formulated in the
early 1990s has stimulated research on long-term effects of early nutrition and environment …
early 1990s has stimulated research on long-term effects of early nutrition and environment …
[HTML][HTML] Accelerated DNA methylation age and medication use among African Americans
DNA methylation age acceleration, the discrepancy between epigenetic age and
chronological age, is associated with mortality and chronic diseases, including diabetes …
chronological age, is associated with mortality and chronic diseases, including diabetes …
Effect of Methotrexate/Vitamin B12 on DNA Methylation as a Potential Factor in Leukemia Treatment-Related Neurotoxicity
VJ Forster, A McDonnell, R Theobald, JA McKay - Epigenomics, 2017 - Taylor & Francis
Methotrexate (MTX) is administered to treat childhood acute lymphoblastic leukemia (ALL). It
acts by inhibiting dihydrofolate reductase which reduces methyltetrahydrofolate, a key …
acts by inhibiting dihydrofolate reductase which reduces methyltetrahydrofolate, a key …
A low glycaemic index diet in pregnancy induces DNA methylation variation in blood of newborns: results from the ROLO randomised controlled trial
AA Geraghty, A Sexton-Oates, EC O'Brien, G Alberdi… - Nutrients, 2018 - mdpi.com
The epigenetic profile of the developing fetus is sensitive to environmental influence.
Maternal diet has been shown to influence DNA methylation patterns in offspring, but …
Maternal diet has been shown to influence DNA methylation patterns in offspring, but …
Dietary inclusion of plant ingredients induces epigenetic changes in the intestine of zebrafish
A Dhanasiri, X Chen, D Dahle, P Siriyappagouder… - Epigenetics, 2020 - Taylor & Francis
Epigenetic modifications, such as DNA methylation, can be regulated by nutrition and
dietary factors. There has been a large increase in the use of sustainable plant-based …
dietary factors. There has been a large increase in the use of sustainable plant-based …
[HTML][HTML] Epigenetic nutraceutical diets in Alzheimer's disease
S Davinelli, V Calabrese, D Zella… - The Journal of nutrition …, 2014 - Elsevier
There is growing support that environmental influences and individual genetic susceptibility
may increase the incidence and accelerate the onset of Alzheimer's disease (AD) …
may increase the incidence and accelerate the onset of Alzheimer's disease (AD) …
The 'golden age'of DNA methylation in neurodegenerative diseases
A Fuso - Clinical chemistry and laboratory medicine, 2013 - degruyter.com
DNA methylation reactions are regulated, in the first instance, by enzymes and the
intermediates that constitute the 'so called'one-carbon metabolism. This is a complex …
intermediates that constitute the 'so called'one-carbon metabolism. This is a complex …