Voriconazole treatment for subacute invasive and chronic pulmonary aspergillosis
H Sambatakou, B Dupont, H Lode… - The American journal of …, 2006 - Elsevier
BACKROUND: Voriconazole is a novel triazole antifungal with a broad spectrum including
Aspergillus species. We conducted an open, noncomparative multicenter study to evaluate …
Aspergillus species. We conducted an open, noncomparative multicenter study to evaluate …
Novel triazole antifungal agents
HL Hoffman, EJ Ernst, ME Klepser - Expert opinion on …, 2000 - Taylor & Francis
The risk of opportunistic infections is greatly increased in patients who are
immunocompromised due to AIDS, cancer chemotherapy and organ or bone marrow …
immunocompromised due to AIDS, cancer chemotherapy and organ or bone marrow …
[HTML][HTML] Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization
G Desoubeaux, C Cray - Frontiers in Microbiology, 2017 - frontiersin.org
Invasive aspergillosis has been studied in laboratory by the means of plethora of distinct
animal models. They were developed to address pathophysiology, therapy, diagnosis, or …
animal models. They were developed to address pathophysiology, therapy, diagnosis, or …
New drugs and novel targets for treatment of invasive fungal infections in patients with cancer
CC Chiou, AH Groll, TJ Walsh - The Oncologist, 2000 - academic.oup.com
Invasive fungal infections have emerged as important causes of morbidity and mortality in
profoundly immunocompromised patients with cancer. Current treatment strategies for these …
profoundly immunocompromised patients with cancer. Current treatment strategies for these …
The search for new triazole antifungal agents
Y Koltin, CA Hitchcock - Current opinion in chemical biology, 1997 - Elsevier
The first generation antifungal agent triazoles, fluconazole and itraconazole, have
revolutionised the treatment of serious fungal infections such as mucosal and invasive …
revolutionised the treatment of serious fungal infections such as mucosal and invasive …
Review of the safety and efficacy of voriconazole
RC Rathbun, HL Hoffman - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Voriconazole is a new triazole antifungal agent structurally related to fluconazole, but with
improved potency and spectrum of activity. Voriconazole has good in vitro activity against …
improved potency and spectrum of activity. Voriconazole has good in vitro activity against …
Voriconazole: therapeutic review of a new azole antifungal
R Herbrecht - Expert review of anti-infective therapy, 2004 - Taylor & Francis
The new triazole antifungal, voriconazole (Vfend®, Pfizer Ltd), was developed for the
treatment of life-threatening fungal infections in immunocompromised patients. The drug …
treatment of life-threatening fungal infections in immunocompromised patients. The drug …
A rapid HPLC assay for voriconazole in human plasma
R Gage, DA Stopher - Journal of pharmaceutical and biomedical analysis, 1998 - Elsevier
This report describes a simple, rapid and reproducible method with a calibration range of 0.2–
10 μg ml− 1 voriconazole in human plasma which is more appropriate for routine clinical use …
10 μg ml− 1 voriconazole in human plasma which is more appropriate for routine clinical use …
Animal models of aspergillosis
G Desoubeaux, C Cray - Comparative Medicine, 2018 - ingentaconnect.com
Aspergillosis is an airborne fungal disease caused by Aspergillus spp., a group of
ubiquitous molds. This disease causes high morbidity and mortality in both humans and …
ubiquitous molds. This disease causes high morbidity and mortality in both humans and …
In vitro evaluation of voriconazole against some clinically important fungi
MR McGinnis, L Pasarell, DA Sutton… - Antimicrobial agents …, 1997 - Am Soc Microbiol
Voriconazole was compared to amphotericin B, fluconazole, and itraconazole by using an in
vitro macrobroth dilution test based upon current National Committee for Clinical Laboratory …
vitro macrobroth dilution test based upon current National Committee for Clinical Laboratory …