Aspergillus species infections are an increasingly common occurrence in hospital wards.
Aspergillus endocarditis constitutes one of the manifestations of the disease, which bears a …

The in vitro activity of BMS-207147 against 80 clinical isolates of Aspergillus was compared
with that of itraconazole and amphotericin B, using a validated microtiter method. Geometric …

OBJECTIVES:: Voriconazole is an antifungal agent structurally related to fluconazole. While
regular drug monitoring is not indicated in most patients, it may help guide dosing in patients …

In vitro susceptibility testing for 50 clinical isolates of fluconazole-susceptible or-resistant
Cryptococcus neoformans was performed with itraconazole and voriconazole. Voriconazole …

Abstract▴ Voriconazole, a broad-spectrum triazole antifungal agent, inhibits the cytochrome
P450-dependent enzyme 14-α-sterol demethylase, thereby disrupting the fungal membrane …

The minimal fungicidal concentrations (MFCs) of voriconazole and itraconazole for five
clinical isolates each of Aspergillus terreus, Aspergillus fumigatus, Aspergillus flavus, and …

Over the past few years, several reports of periostitis affecting patients treated with
voriconazole appeared in the literature. As rheumatologists are likely to be called to see …

We studied the in vitro activity of voriconazole (VCZ) itraconazole (ITZ) and amphotericin B
(AMB) against 216 clinical isolates of Aspergillus spp.(142 Aspergillus fumigatus and 74 …

We compared the efficacies of amphotericin B and voriconazole against invasive pulmonary
aspergillosis in a guinea-pig model. A susceptible isolate of Aspergillus fumigatus was used …

The changing epidemiology and therapy of nosocomial candidemia are discussed. The
frequency of nosocomial bloodstream infections by Candida species has risen dramatically …