Advancements in nanoparticle-based treatment approaches for skin cancer therapy

L Zeng, BHJ Gowda, MG Ahmed, MAS Abourehab… - Molecular Cancer, 2023 - Springer
Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a
burden on global health and the economy. The enormously rising environmental changes …

Design principles of microneedles for drug delivery and sampling applications

Z Le, J Yu, YJ Quek, B Bai, X Li, Y Shou, B Myint, C Xu… - Materials Today, 2023 - Elsevier
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Microneedle patch loaded with exosomes containing microRNA‐29b prevents cardiac fibrosis after myocardial infarction

J Yuan, H Yang, C Liu, L Shao, H Zhang… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is a cardiovascular disease that poses a serious threat to human
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …

Microneedle biomedical devices

M Zheng, T Sheng, J Yu, Z Gu, C Xu - Nature Reviews Bioengineering, 2024 - nature.com
Microneedle (MN) technologies have gained interest for biomedical applications, ranging
from drug delivery to sensing and tissue sampling in skin and internal organs. The …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

Engineered Lactococcus lactis secreting Flt3L and OX40 ligand for in situ vaccination-based cancer immunotherapy

J Zhu, Y Ke, Q Liu, J Yang, F Liu, R Xu, H Zhou… - Nature …, 2022 - nature.com
In situ vaccination is a promising strategy to convert the immunosuppressive tumor
microenvironment into an immunostimulatory one with limited systemic exposure and side …

Triggered release of antimicrobial peptide from microneedle patches for treatment of wound biofilms

Y Su, SM Andrabi, SMS Shahriar, SL Wong… - Journal of Controlled …, 2023 - Elsevier
Biofilms pose a great challenge for wound management. Herein, this study describes a near-
infrared (NIR) light-responsive microneedle patch for on-demand release of antimicrobial …

Research progress of advanced microneedle drug delivery system and its application in biomedicine

R Zhang, Q Miao, D Deng, J Wu, Y Miao, Y Li - Colloids and Surfaces B …, 2023 - Elsevier
Transdermal drug delivery is an effective way of drug delivery in addition to oral and
intravenous administration. Among them, microneedle administration is a new type of …

Microneedles as a momentous platform for psoriasis therapy and diagnosis: A state-of-the-art review

BHJ Gowda, MG Ahmed, U Hani, P Kesharwani… - International Journal of …, 2023 - Elsevier
Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

An overview of topical lipid-based and polymer-based nanocarriers for treatment of psoriasis

SA Hazari, H Kaur, R Karwasra… - International Journal of …, 2023 - Elsevier
Psoriasis is a consistently recurring, inflammatory skin disease, affecting about 2-5% of the
world population. Different types of psoriasis can be observed such as guttate psoriasis …