[HTML][HTML] Severe COVID-19 and aging: are monocytes the key?

BD Pence - Geroscience, 2020 - Springer
The ongoing pandemic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
causes a disproportionate number of severe cases and deaths in older adults. Severe SARS …

[HTML][HTML] Potential therapeutic targets and vaccine development for SARS-CoV-2/COVID-19 pandemic management: a review on the recent update

U Anand, S Jakhmola, O Indari, HC Jha… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly pathogenic
novel virus that has caused a massive pandemic called coronavirus disease 2019 (COVID …

[HTML][HTML] State of the art of 18F-FDG PET/CT application in inflammation and infection: a guide for image acquisition and interpretation

M Casali, C Lauri, C Altini, F Bertagna… - Clinical and …, 2021 - Springer
Aim The diagnosis, severity and extent of a sterile inflammation or a septic infection could be
challenging since there is not one single test able to achieve an accurate diagnosis. The …

[HTML][HTML] SARS-CoV-2 nucleocapsid protein targets RIG-I-like receptor pathways to inhibit the induction of interferon response

SJ Oh, OS Shin - Cells, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the coronavirus disease 2019 (COVID-19) that has resulted in the current pandemic. The …

[HTML][HTML] Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional …

AM Gamage, KS Tan, WOY Chan, J Liu, CW Tan… - PLoS …, 2020 - journals.plos.org
The novel coronavirus SARS-CoV-2 is the causative agent of Coronavirus Disease 2019
(COVID-19), a global healthcare and economic catastrophe. Understanding of the host …

[HTML][HTML] Dual nature of type I interferons in SARS-CoV-2-induced inflammation

C King, J Sprent - Trends in immunology, 2021 - cell.com
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The ability of our cells to secrete type I …

[HTML][HTML] Asymptomatic SARS-CoV-2 carriers: a systematic review and meta-analysis

G Syangtan, S Bista, P Dawadi… - Frontiers in public …, 2021 - frontiersin.org
Asymptomatic cases of SARS-CoV-2 can be unknown carriers magnifying the transmission
of COVID-19. This study appraised the frequency of asymptomatic individuals and estimated …

[HTML][HTML] Progress and pitfalls in the quest for effective SARS-CoV-2 (COVID-19) vaccines

KL Flanagan, E Best, NW Crawford, M Giles… - Frontiers in …, 2020 - frontiersin.org
There are currently around 200 SARS-CoV-2 candidate vaccines in preclinical and clinical
trials throughout the world. The various candidates employ a range of vaccine strategies …

Immune dysregulation and system pathology in COVID-19

M Jamal, HI Bangash, M Habiba, Y Lei, T Xie, J Sun… - Virulence, 2021 - Taylor & Francis
ABSTRACT The coronavirus disease 19 (COVID-19) caused by the novel coronavirus
known as SARS-CoV-2 has caused a global public health crisis. As of 7 January 2021 …

Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation

L Wallentin, J Lindbäck, N Eriksson… - European heart …, 2020 - academic.oup.com
Aims The global COVID-19 pandemic is caused by the SARS-CoV-2 virus entering human
cells using angiotensin-converting enzyme 2 (ACE2) as a cell surface receptor. ACE2 is …