In their recent letter, Gonzalez et al. discuss the safety of using universal stem cells in
regenerative medicine (Gonzalez et al., 2020). The term ''universal''conveys that the cells …

Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy and
the fourth leading cause of cancer-related deaths globally. HCC is often diagnosed in late …

The clinically restored blood supply post myocardial infarction (MI) will break the
physiological and metabolic balance of the ischemic myocardial region, leading to a new …

Viral myocarditis (VMC), commonly caused by coxsackievirus B3 (CVB3) infection, lacks
specific treatments and leads to serious heart conditions. Current treatments, such as IFNα …

We seek to demonstrate whether therapeutic efficacy can be improved by combination of
repeated intravenous administration and local transplantation of human induced …

The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …

Cystic Fibrosis (CF) is a chronic autosomal recessive disease caused by defects in the cystic
fibrosis transmembrane conductance regulator gene (CFTR). Cystic Fibrosis affects multiple …

The field of cell and gene therapy (CGT) is maturing at a rapid rate. Manufacturing remains a
major challenge and manufacturing failures and limitations are a notable source of CGT …

Stem cell replacement holds the potential for sensorineural hearing loss (SNHL) treatment.
However, its translation into clinical practice requires strategies for improving stem cell …

Background The human induced pluripotent stem cells (hiPSCs) can generate all the cells
composing the human body, theoretically. Therefore, hiPSCs are thought to be a candidate …