Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Platelets produce platelet growth factors such as PDGF, IGF-1, EGF-, HGF, TGFβ, bFGF, and
VEGF, which are crucial in regulating all stages of the wound healing process. The source of …

Deciding when to return to sport after injury is complex and multifactorial—an exercise in risk
management. Return to sport decisions are made every day by clinicians, athletes and …

Background: Platelet-rich plasma (PRP) is a blood-derived preparation whose use has
grown exponentially in orthopaedic practice. However, there remains an unclear …

Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Abstract Purpose of Review This review evaluates current clinical literature on the use of
platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP …

Purpose To determine (1) whether platelet-rich plasma (PRP) injection significantly
improves validated patient-reported outcomes in patients with symptomatic knee …

The clinical application of platelet-rich plasma (PRP) and other regenerative therapies in
sports, spine, and musculoskeletal medicine has soared in the last decade. Over this period …

Traumatic muscle injury represents a collection of skeletal muscle pathologies caused by
trauma to the muscle tissue and is defined as damage to the muscle tissue that can result in …

Osteoarthritis (OA) is a degenerative disease involving joint damage, an inadequate healing
response and progressive deterioration of the joint architecture that commonly affects the …