Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

The recent pandemic of the novel coronavirus disease 2019 (COVID‐19) has caused huge
worldwide disruption due to the lack of available testing locations and equipment. The use of …

Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …

Although the concept of selective delivery has been postulated over 100 years ago, no
targeted nanomedicine has been clinically approved so far. Nanoparticles modified with …

Complex molecular and metabolic phenotypes depict cancers as a constellation of different
diseases with common themes. Precision imaging of such phenotypes requires flexible and …

Molecular image-guided surgery has the potential for translating the tools of molecular
pathology to real-time guidance in surgery. As a whole, there are incredibly positive …

Identification of lymph node (LN) metastasis is essential for staging of solid tumors, and as a
result, surgeons focus on harvesting significant numbers of LNs during ablative procedures …

The emerging biological understanding of metastatic cancer and proof-of-concept clinical
trials suggest that debulking all gross disease holds great promise for improving patient …

Intraoperative identification of carcinoma at lumpectomy margins would enable reduced re-
excision rates, which are currently as high as 20% to 50%. Although imaging of disease …

The completion of surgical resection is a key prognostic factor in brain tumor treatment. This
requires surgeons to identify residual tumors in theater as well as to margin the proximity of …