Head and neck squamous cell carcinomas (HNSCCs) have high levels of chromosomal
instability and epidermal growth factor receptor (EGFR) overexpression, both of which drive …

Due to clinical concerns about gadolinium toxicity, there is growing interest in the
development of alternative contrast agents for magnetic resonance imaging (MRI). Recently …

An intraoperative approach for breast tumor-margin assessment is presented, using a kinetic
model for surface-enhanced Raman scattering nanoparticles (SERS NPs). A numerical …

A wide range of factors can influence the quality of data obtained through detection and/or
imaging of optical molecular probe uptake and retention in biological tissue. With so many …

Tissue biopsies, where a volume of tissue is removed from a patient, typically through
needle extraction, provides critical information about the cellular and molecular aspects of …

The status of lymph node is considered a critical prognostic factor for staging and guiding
the future adjuvant treatment in many cancer types. The estimation of undetected …

Sentinel lymph node biopsy is a good prognostic factor for several cancers as therapeutic
decisions are often determined by the results. Despite this importance, false negatives …

Ligands are compounds that generally bind specifically to a receptor. The chemistry of
Ligand–Receptor interactions implies some restrictions: in the control mechanisms of …

Cancer imaging is useful for multiple clinical and research purposes such as diagnostics,
surgery guidance, monitoring disease progression, and metastasis detection. In particular …