Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Chlamydia cell biology and pathogenesis

C Elwell, K Mirrashidi, J Engel - Nature Reviews Microbiology, 2016 - nature.com
Chlamydia spp. are important causes of human disease for which no effective vaccine
exists. These obligate intracellular pathogens replicate in a specialized membrane …

[HTML][HTML] Chlamydia trachomatis genital infections

CM O'Connell, ME Ferone - Microbial cell, 2016 - ncbi.nlm.nih.gov
Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of
bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes …

[HTML][HTML] Salmonella manipulation of host signaling pathways provokes cellular transformation associated with gallbladder carcinoma

T Scanu, RM Spaapen, JM Bakker, CB Pratap, L Wu… - Cell host & …, 2015 - cell.com
Cancer is fueled by deregulation of signaling pathways in control of cellular growth and
proliferation. These pathways are also targeted by infectious pathogens en route to …

The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer

SS Savant, S Sriramkumar, HM O'Hagan - Cancers, 2018 - mdpi.com
Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …

The cervicovaginal microbiota-host interaction modulates Chlamydia trachomatis infection

VL Edwards, SB Smith, EJ McComb, J Tamarelle, B Ma… - MBio, 2019 - Am Soc Microbiol
The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

A Gagnaire, B Nadel, D Raoult, J Neefjes… - Nature Reviews …, 2017 - nature.com
Infections are estimated to contribute to 20% of all human tumours. Viruses are known to
induce cell transformation, but evidence has also linked bacteria, such as Helicobacter …

Bacterial‐Mediated Tumor Therapy: Old Treatment in a New Context

Y Liu, L Niu, N Li, Y Wang, M Liu, X Su, X Bao… - Advanced …, 2023 - Wiley Online Library
Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …

Streptococcus pneumoniae secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

P Rai, M Parrish, IJJ Tay, N Li… - Proceedings of the …, 2015 - National Acad Sciences
Streptococcus pneumoniae is a leading cause of pneumonia and one of the most common
causes of death globally. The impact of S. pneumoniae on host molecular processes that …

Antibiotics use and subsequent risk of colorectal cancer: a Swedish nationwide population-based study

SSM Lu, Z Mohammed, C Häggström… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Antibiotics use may increase colorectal cancer (CRC) risk by altering the gut
microbiota, with suggestive evidence reported. Our study aims to investigate antibiotics use …