Thyroid autoimmune disorders and cancer

SM Ferrari, P Fallahi, G Elia, F Ragusa, I Ruffilli… - Seminars in cancer …, 2020 - Elsevier
In the last decades, many studies conducted in vitro, and in vivo, have shown that thyroid
autoimmunity and thyroid cancer (TC)(mainly papillary TC) can be concomitant, even if the …

[HTML][HTML] Pathogenesis, diagnosis and management of thyroid nodules in children

M Niedziela - Endocrine-related cancer, 2006 - erc.bioscientifica.com
According to the literature thyroid nodules are quite rare in the first two decades of life.
However, there are some exceptions, relating to areas with an iodine deficiency or affected …

BRAF mutation in papillary thyroid carcinoma

Y Cohen, M Xing, E Mambo, Z Guo… - Journal of the …, 2003 - academic.oup.com
The BRAF gene has been found to be activated by mutation in human cancers,
predominantly in malignant melanoma. We tested 476 primary tumors, including 214 lung …

Analysis of the rising incidence of thyroid cancer using the Surveillance, Epidemiology and End Results national cancer data registry

JD Cramer, P Fu, KC Harth, S Margevicius, SM Wilhelm - Surgery, 2010 - Elsevier
BACKGROUND: The incidence of thyroid cancer has more than doubled in recent decades.
Debate continues on whether the increasing incidence is a result of an increased detection …

[HTML][HTML] Association between Hashimoto's thyroiditis and thyroid cancer in 64,628 patients

C Resende de Paiva, C Grønhøj… - Frontiers in …, 2017 - frontiersin.org
Background The incidence of thyroid cancer (TC) is increasing although explanatory causes
are lacking. A link between cancer and inflammation is well documented but unclear for …

[HTML][HTML] LncRNA SNHG15 acts as a ceRNA to regulate YAP1-Hippo signaling pathway by sponging miR-200a-3p in papillary thyroid carcinoma

DM Wu, S Wang, X Wen, XR Han, YJ Wang… - Cell death & …, 2018 - nature.com
Over the past decade, lncRNAs have been widely reported in human malignant tumors,
including papillary thyroid carcinoma. LncRNA SNHG15 has been validated to be a tumor …

Nasopharyngeal carcinoma—review of the molecular mechanisms of tumorigenesis

J Chou, YC Lin, J Kim, L You, Z Xu… - Head & Neck …, 2008 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is a head and neck cancer rare throughout most of the
world but common in certain geographic areas, such as southern Asia. While environmental …

High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines

X Xu, RM Quiros, P Gattuso, KB Ain, RA Prinz - Cancer research, 2003 - AACR
Abstract The RAS-RAF-MEK-ERK-MAP kinase pathway mediates the cellular response to
extracellular signals that regulate cell proliferation, differentiation, and apoptosis. Mutation of …

Molecular pathogenesis of euthyroid and toxic multinodular goiter

K Krohn, D Fuhrer, Y Bayer, M Eszlinger… - Endocrine …, 2005 - academic.oup.com
The purpose of this review is to summarize current knowledge of the etiology of euthyroid
and toxic multinodular goiter (MNG) with respect to the epidemiology, clinical characteristics …

Tumorigenic and metastatic activity of human thyroid cancer stem cells

M Todaro, F Iovino, V Eterno, P Cammareri… - Cancer research, 2010 - AACR
Thyroid carcinoma is the most common endocrine malignancy and the first cause of death
among endocrine cancers. We show that the tumorigenic capacity in thyroid cancer is …