Curcumin, the active substance of turmeric: its effects on health and ways to improve its bioavailability

ME Abd El‐Hack, MT El‐Saadony… - Journal of the …, 2021 - Wiley Online Library
Turmeric (Curcuma longa L.) is a spice utilized widely in India, China, and Southeast Asia as
an aromatic stimulant, a food preservative, and coloring material. The commonly used …

[HTML][HTML] The role of curcumin in aging and senescence: Molecular mechanisms

A Zia, T Farkhondeh, AM Pourbagher-Shahri… - Biomedicine & …, 2021 - Elsevier
Healthy aging and human longevity are intricate phenotypes affected by environmental
factors such as physical exercise, diet, health habits, and psychosocial situations as well as …

[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
Cancer is a condition where the body cells multiply in an uncontrollable manner.
Chemoprevention of cancer is a broad term that describes the involvement of external …

Activators and inhibitors of NRF2: a review of their potential for clinical development

N Robledinos-Antón… - Oxidative medicine …, 2019 - Wiley Online Library
The transcription factor NRF2 (nuclear factor erythroid 2‐related factor 2) triggers the first
line of homeostatic responses against a plethora of environmental or endogenous …

[HTML][HTML] Curcumin, a natural antimicrobial agent with strain-specific activity

A Adamczak, M Ożarowski, TM Karpiński - Pharmaceuticals, 2020 - mdpi.com
Curcumin, a principal bioactive substance of turmeric (Curcuma longa L.), is reported as a
strong antioxidant, anti-inflammatory, antibacterial, antifungal, and antiviral agent. However …

[HTML][HTML] Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …

The therapeutic potential of curcumin: A review of clinical trials

B Salehi, Z Stojanović-Radić, J Matejić… - European journal of …, 2019 - Elsevier
Curcuma longa L., its derived extracts and even its major compound curcumin has a long
history of use and doubtless effectiveness, reported through increasingly detailed in vitro, ex …

[HTML][HTML] Effectiveness of curcumin on outcomes of hospitalized COVID-19 patients: A systematic review of clinical trials

A Vahedian-Azimi, M Abbasifard, F Rahimi-Bashar… - Nutrients, 2022 - mdpi.com
Despite the ongoing vaccination efforts, there is still an urgent need for safe and effective
treatments to help curb the debilitating effects of COVID-19 disease. This systematic review …

[HTML][HTML] Antimicrobial potential of curcumin: therapeutic potential and challenges to clinical applications

Y Hussain, W Alam, H Ullah, M Dacrema, M Daglia… - Antibiotics, 2022 - mdpi.com
Curcumin is a bioactive compound that is extracted from Curcuma longa and that is known
for its antimicrobial properties. Curcuminoids are the main constituents of curcumin that …

[HTML][HTML] Inflammation and oxidative stress in chronic kidney disease—potential therapeutic role of minerals, vitamins and plant-derived metabolites

SF Rapa, BR Di Iorio, P Campiglia, A Heidland… - International journal of …, 2019 - mdpi.com
Chronic kidney disease (CKD) is a debilitating pathology with various causal factors,
culminating in end stage renal disease (ESRD) requiring dialysis or kidney transplantation …