[HTML][HTML] The Th17 lineage: from barrier surfaces homeostasis to autoimmunity, cancer, and HIV-1 pathogenesis

VS Wacleche, A Landay, JP Routy, P Ancuta - Viruses, 2017 - mdpi.com
The T helper 17 (Th17) cells represent a subset of CD4+ T-cells with unique effector
functions, developmental plasticity, and stem-cell features. Th17 cells bridge innate and …

[HTML][HTML] Inflammatory and immunometabolic consequences of gut dysfunction in HIV: parallels with IBD and implications for reservoir persistence and non-AIDS …

J Alzahrani, T Hussain, D Simar, R Palchaudhuri… - …, 2019 - thelancet.com
The gastrointestinal mucosa is critical for maintaining the integrity and functions of the gut.
Disruption of this barrier is a hallmark and a risk factor for many intestinal and chronic …

[HTML][HTML] Associations of body mass index at different ages with early-onset colorectal cancer

H Li, D Boakye, X Chen, L Jansen, J Chang-Claude… - Gastroenterology, 2022 - Elsevier
Background & Aims Incidence of colorectal cancer (CRC) in younger adults is increasing in
many countries. Given the established association of body mass index (BMI) with CRC risk …

[PDF][PDF] Anti-apoptotic protein BIRC5 maintains survival of HIV-1-infected CD4+ T cells

HH Kuo, R Ahmad, GQ Lee, C Gao, HR Chen… - Immunity, 2018 - cell.com
Summary HIV-1 infection of CD4+ T cells leads to cytopathic effects and cell demise, which
is counter to the observation that certain HIV-1-infected cells possess a remarkable long …

Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling

JJ Kibbie, SM Dillon, TA Thompson, CM Purba… - Immunobiology, 2021 - Elsevier
An important function of the gut microbiome is the fermentation of non-digestible dietary
fibers into short chain fatty acids (SCFAs). The three primary SCFAs: acetate, propionate …

Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID‐19 severity

CAS Prado, DLM Fonseca, Y Singh… - Journal of Medical …, 2023 - Wiley Online Library
Several perturbations in the number of peripheral blood leukocytes, such as neutrophilia
and lymphopenia associated with Coronavirus disease 2019 (COVID‐19) severity, point to …

Relationship between human immunodeficiency virus (HIV-1) infection and chronic periodontitis

TLS Pólvora, ÁVV Nobre, C Tirapelli… - Expert review of …, 2018 - Taylor & Francis
Introduction: Current studies show that, even in the era of antiretroviral therapies, HIV-1
infection is associated with more severe and frequent refractory chronic periodontitis. Areas …

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques

Y Sui, A Dzutsev, D Venzon, B Frey, V Thovarai… - Mucosal …, 2018 - nature.com
It is unknown whether the gut microbiome affects HIV transmission. In our recent SHIV
vaccine study, we found that the naive rhesus macaques from two different sources had …

New Th17-specific therapeutic strategies for HIV remission

D Planas, JP Routy, P Ancuta - Current Opinion in HIV and AIDS, 2019 - journals.lww.com
New Th17-specific therapeutic strategies for HIV remission : Current Opinion in HIV and AIDS
New Th17-specific therapeutic strategies for HIV remission : Current Opinion in HIV and AIDS …

[HTML][HTML] SARS-CoV-2 and Prevotella spp.: friend or foe? A systematic literature review

Z Tamanai-Shacoori… - Journal of Medical …, 2022 - microbiologyresearch.org
During this global pandemic of the COVID-19 disease, a lot of information has arisen in the
media and online without scientific validation, and among these is the possibility that this …