Drug loading techniques for exosome-based drug delivery systems

XM Xi, SJ Xia, R Lu - Die Pharmazie-An International Journal …, 2021 - ingentaconnect.com
Exosomes are bilayer membrane-coated extracellular vesicles measuring between 40 and
100 nm in diameter. As a natural carrier, exosomes have the advantages of low …

Bone‐a‐petite: engineering exosomes towards bone, osteochondral, and cartilage repair

HP Bei, PM Hung, HL Yeung, S Wang, X Zhao - Small, 2021 - Wiley Online Library
Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …

Exosomes as a next-generation drug delivery system: An update on drug loading approaches, characterization, and clinical application challenges

F Mehryab, S Rabbani, S Shahhosseini, F Shekari… - Acta biomaterialia, 2020 - Elsevier
Exosomes are small nanoparticles secreted by almost all cells and have a well-known role
in intercellular communication. They are found in different body fluids and can also be …

Roles of extracellular vesicles in the aging microenvironment and age‐related diseases

Y Yin, H Chen, Y Wang, L Zhang… - Journal of extracellular …, 2021 - Wiley Online Library
Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …

[HTML][HTML] Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Exosomes as potential functional nanomaterials for tissue engineering

Y Yao, Y Jiang, J Song, R Wang, Z Li… - Advanced …, 2023 - Wiley Online Library
Exosomes are cell‐derived extracellular vesicles of 40–160 nm diameter, which carry
numerous biomolecules and transmit information between cells. They are used as functional …

[HTML][HTML] Exosomes derived from miR-126-3p-overexpressing synovial fibroblasts suppress chondrocyte inflammation and cartilage degradation in a rat model of …

Y Zhou, J Ming, Y Li, B Li, M Deng, Y Ma, Z Chen… - Cell Death …, 2021 - nature.com
MicroRNAs (miRNAs) encapsulated within exosomes can serve as essential regulators of
intercellular communication and represent promising biomarkers of several aging …

[HTML][HTML] Enhancement of the therapeutic efficacy of mesenchymal stem cell-derived exosomes in osteoarthritis

Z Zhang, S Zhao, Z Sun, C Zhai, J Xia, C Wen… - Cellular & Molecular …, 2023 - Springer
Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main
pathological change, is the major source of pain and disability worldwide. Despite current …

[HTML][HTML] Harnessing exosomes as cutting-edge drug delivery systems for revolutionary osteoarthritis therapy

J Lu, Y Zhang, X Yang, H Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Exosomes, remarkable extracellular vesicles, have emerged as an advanced frontier in
intercellular communication. This remarkable capacity positions them as promising …

[HTML][HTML] Emerging role of exosomes in craniofacial and dental applications

X Xing, S Han, Z Li, Z Li - Theranostics, 2020 - ncbi.nlm.nih.gov
Exosomes, a specific subgroup of extracellular vesicles that are secreted by cells, have
been recognized as important mediators of intercellular communication. They participate in …