[HTML][HTML] Regulated cell death (RCD) in cancer: key pathways and targeted therapies

F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

[HTML][HTML] Natural products as chemo-radiation therapy sensitizers in cancers

S Nisar, T Masoodi, KS Prabhu, S Kuttikrishnan… - Biomedicine & …, 2022 - Elsevier
Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

[HTML][HTML] Pyrimidine biosynthetic enzyme CAD: its function, regulation, and diagnostic potential

G Li, D Li, T Wang, S He - International Journal of Molecular Sciences, 2021 - mdpi.com
CAD (Carbamoyl-phosphate synthetase 2, Aspartate transcarbamoylase, and
Dihydroorotase) is a multifunctional protein that participates in the initial three speed-limiting …

[HTML][HTML] Dietary polyphenols: promising adjuvants for colorectal cancer therapies

L Bracci, A Fabbri, M Del Corno, L Conti - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is a leading cause of death worldwide. Despite the
development of novel surgical and therapeutic strategies, 50% of patients relapse after …

[HTML][HTML] Therapeutic potential of naturally occurring small molecules to target the wnt/β-catenin signaling pathway in colorectal cancer

LFS Oliveira, D Predes, HL Borges, JG Abreu - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is an emerging public health problem and the
second leading cause of death worldwide, with a significant socioeconomic impact in …

Bioactive food components for colorectal cancer prevention and treatment: A good match

S Amintas, C Dupin, J Boutin, P Beaumont… - Critical reviews in …, 2023 - Taylor & Francis
Colorectal cancer (CRC) is the third most frequent cancer worldwide, accounts for about
10% of the total cancer cases, and ranks as the second cause of death by cancer. CRC is …

[PDF][PDF] A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in …

M Kroon, HWM Van Laarhoven, EL Swart, EM Kemper… - Heliyon, 2023 - cell.com
Background The spice curcumin is supposed to have many different beneficial health
effects. To understand the complete pharmacokinetics of curcumin we need an analytical …

The triangular relationship between traditional Chinese medicines, intestinal flora, and colorectal cancer

Y Zou, S Wang, H Zhang, Y Gu, H Chen… - Medicinal Research …, 2024 - Wiley Online Library
Over the past decade, colorectal cancer has reported a higher incidence in younger adults
and a lower mortality rate. Recently, the influence of the intestinal flora in the initiation …

[HTML][HTML] Combination Chemotherapy with Selected Polyphenols in Preclinical and Clinical Studies—An Update Overview

C Jakobušić Brala, A Karković Marković, A Kugić… - Molecules, 2023 - mdpi.com
This review article describes studies published over the past five years on the combination
of polyphenols, which are the most studied in the field of anticancer effects (curcumin …