Our globin census update allows us to refine our vision of globin origin, evolution, and
structure to function relationship in the context of the currently accepted tree of life. The …

Despite recent advances in melanoma treatment, there are still patients that either do not
respond or develop resistance. This unresponsiveness and/or acquired resistance to …

Asthenozoospermia is one of the main factors leading to male infertility, but the genetic
mechanisms have not been fully elucidated. Variants in the androglobin (ADGB) gene were …

In the decade since the discovery of androglobin, a multi-domain hemoglobin of metazoans
associated with ciliogenesis and spermatogenesis, there has been little advance in the …

The current restrictive criteria for gasotransmitters exclude oxygen (O2) as a gasotransmitter
in vertebrates. In this manuscript, I propose a revision of gasotransmitter criteria to include …

Background Inhibitors of DNA binding (ID) proteins mainly inhibit gene expression and
regulate cell fate decisions by interacting with E‐proteins. All four ID proteins (ID1–4) are …

Cytoglobin (CYGB) is a member of the oxygen-binding globin superfamily. In this study we
generated stable CYGB overexpressing A375 melanoma cells and performed RNA …

Objectives In male mice, adgb‐knockout has been reported to cause male infertility with
spermatogenesis defects involving flagella and acrosome. However, this remains unclear for …

Androglobin (ADGB) is a highly conserved and recently identified member of the globin
superfamily. Although previous studies revealed a link to ciliogenesis and an involvement in …

Globins have been studied as model proteins to elucidate the principles of protein evolution.
This was achieved by understanding the relationship between amino acid sequence, three …