Long noncoding RNAs in cancer metastasis
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …
multistep process that occurs through the acquisition of molecular and phenotypic changes …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
[HTML][HTML] LncRNA MALAT1 promotes osteoarthritis by modulating miR-150-5p/AKT3 axis
Y Zhang, F Wang, G Chen, R He, L Yang - Cell & bioscience, 2019 - Springer
Background Many studies have reported that long noncoding RNAs (lncRNAs) could act as
sponges for microRNAs (miRNAs) and play important roles in the regulation of osteoarthritis …
sponges for microRNAs (miRNAs) and play important roles in the regulation of osteoarthritis …
[HTML][HTML] Identification of CDK2-related immune forecast model and ceRNA in lung adenocarcinoma, a pan-cancer analysis
TT Liu, R Li, C Huo, JP Li, J Yao, X Ji… - Frontiers in cell and …, 2021 - frontiersin.org
Background Tumor microenvironment (TME) plays important roles in different cancers. Our
study aimed to identify molecules with significant prognostic values and construct a relevant …
study aimed to identify molecules with significant prognostic values and construct a relevant …
Epithelial–mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?
J van Staalduinen, D Baker, P Ten Dijke, H van Dam - Oncogene, 2018 - nature.com
Chemoresistance remains a major complication of cancer treatments. Recent data provide
strong evidence that chemoresistance is linked to epithelial–mesenchymal transition (EMT) …
strong evidence that chemoresistance is linked to epithelial–mesenchymal transition (EMT) …
[HTML][HTML] The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element
O Marín-Béjar, AM Mas, J González, D Martinez… - Genome biology, 2017 - Springer
Background It is now obvious that the majority of cellular transcripts do not code for proteins,
and a significant subset of them are long non-coding RNAs (lncRNAs). Many lncRNAs show …
and a significant subset of them are long non-coding RNAs (lncRNAs). Many lncRNAs show …
[HTML][HTML] ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling
Y He, HQ Yue, Y Cheng, Z Ding, Z Xu, C Lv… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) are regarded as crucial regulators in tumor progression.
Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 …
Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 …
[HTML][HTML] Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR …
S Li, J Zhou, Z Wang, P Wang, X Gao… - Biomedicine & …, 2018 - Elsevier
Triple-negative breast cancer (TNBC) is considered to be the most aggressive and lethal
type of breast cancer. Many studies have suggested that the dysfunction of long noncoding …
type of breast cancer. Many studies have suggested that the dysfunction of long noncoding …
[HTML][HTML] Identification and validation of ferroptosis-related LncRNA signatures as a novel prognostic model for colon cancer
Z Wu, Z Lu, L Li, M Ma, F Long, R Wu, L Huang… - Frontiers in …, 2022 - frontiersin.org
Background Ferroptosis is a newly defined form of programmed cell death that plays an
important role in many cancers. However, ferroptosis-related lncRNAs (FRLs) involved in the …
important role in many cancers. However, ferroptosis-related lncRNAs (FRLs) involved in the …
[HTML][HTML] Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
X Lu, Q Xu, Y Tong, Z Zhang, G Dun, Y Feng, J Tang… - Cell Reports, 2022 - cell.com
Both Fusobacterium nucleatum (F. nucleatum) and long non-coding RNA (lncRNA) EVADR
are associated with colorectal cancer (CRC), but their relationship with CRC metastasis and …
are associated with colorectal cancer (CRC), but their relationship with CRC metastasis and …