[HTML][HTML] Natural products and derivatives for breast cancer treatment: From drug discovery to molecular mechanism

J Zhang, Y Wu, Y Li, S Li, J Liu, X Yang, G Xia, G Wang - Phytomedicine, 2024 - Elsevier
Background Breast cancer stands as the most common malignancy among women globally
and a leading cause of cancer-related mortality. Conventional treatments, such as surgery …

Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K/Akt/mTOR signaling …

A Iranpanah, MB Majnooni, H Biganeh… - Phytotherapy …, 2024 - Wiley Online Library
Recently, malignant neoplasms have growingly caused human morbidity and mortality.
Head and neck cancer (HNC) constitutes a substantial group of malignancies occurring in …

Phloridzin docosahexaenoate inhibits spheroid formation by breast cancer stem cells and exhibits cytotoxic effects against paclitaxel-resistant triple negative breast …

W Fernando, RF Clark, HPV Rupasinghe… - International Journal of …, 2023 - mdpi.com
The eradication of cancer stem cells (CSCs) is vital to successful cancer treatment and
overall disease-free survival. CSCs are a sub-population of cells within a tumor that are …

Hydroxytyrosol Counteracts Triple Negative Breast Cancer Cell Dissemination via Its Copper Complexing Properties

N Perta, L Torrieri Di Tullio, E Cugini, P Fattibene… - Biology, 2023 - mdpi.com
Simple Summary Several naturally occurring substances, known as polyphenols, may be
found in a variety of plant-based foods and drinks, including fruits, vegetables, whole grains …

Cellular electrophysiological effects of the citrus flavonoid hesperetin in dog and rabbit cardiac ventricular preparations

ASA Mohammed, G Mohácsi, M Naveed, J Prorok… - Scientific Reports, 2024 - nature.com
Recent experimental data shows that hesperetin, a citrus flavonoid, affects potassium
channels and can prolong the QTc interval in humans. Therefore, in the present study we …

Lemon peel-based fluorescent carbon quantum dots as a functional filler in polyvinyl alcohol-based films for active packaging applications

A Jayakumar, S Radoor, GH Shin, JT Kim - Industrial Crops and Products, 2024 - Elsevier
Carbonation of agro-waste into high-value-added products is becoming a promising strategy
for producing functional active materials and for reducing landfills. Carbon quantum dots …

[HTML][HTML] Machine learning for polyphenol-based materials

S Jiang, P Yang, Y Zheng, X Lu, C Xie - Smart Materials in Medicine, 2024 - Elsevier
Polyphenol-based materials, primarily composed of polyphenolic compounds, have
attracted considerable attention due to their unique chemical structures and biological …

Cold atmospheric plasma modified polycaprolactone solution prior to electrospinning: A novel approach for improving quercetin-loaded nanofiber drug delivery …

YE Bulbul, AU Oksuz - International Journal of Pharmaceutics, 2024 - Elsevier
In this study, we present a novel approach for enhancing the performance of Quercetin-
loaded nanofiber drug delivery systems through the modification of Polycaprolactone (PCL) …

Apigenin: Molecular Mechanisms and Therapeutic Potential against Cancer Spreading

V Naponelli, MT Rocchetti, D Mangieri - International Journal of …, 2024 - mdpi.com
Due to its propensity to metastasize, cancer remains one of the leading causes of death
worldwide. Thanks in part to their intrinsic low cytotoxicity, the effects of the flavonoid family …

Potential of Natural Phenolic Compounds against Doxorubicin-Induced Chemobrain: Biological and Molecular Mechanisms Involved

S Serini, G Calviello - Antioxidants, 2024 - mdpi.com
Chemotherapy-induced cognitive impairment or “chemobrain” is a prevalent long-term
complication of chemotherapy and one of the more devastating. Most of the studies …